Prediction model for obstetric anal sphincter injury using machine learning

Henry Hillel Chill, Joshua Guedalia, Michal Lipschuetz, Tzvika Shimonovitz, Ron Unger, David Shveiky, Gilad Karavani

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

Introduction and hypothesis: Obstetric anal sphincter injury (OASI) is a complication with substantial maternal morbidity. The aim of this study was to develop a machine learning model that would allow a personalized prediction algorithm for OASI, based on maternal and fetal variables collected at admission to labor. Materials and methods: We performed a retrospective cohort study at a tertiary university hospital. Included were term deliveries (live, singleton, vertex). A comparison was made between women diagnosed with OASI and those without such injury. For formation of a machine learning-based model, a gradient boosting machine learning algorithm was implemented. Evaluation of the performance model was achieved using the area under the receiver-operating characteristic curve (AUC). Results: Our cohort comprised 98,463 deliveries, of which 323 (0.3%) were diagnosed with OASI. Applying a machine learning model to data recorded during admission to labor allowed for individualized risk assessment with an AUC of 0.756 (95% CI 0.732–0.780). According to this model, a lower number of previous births, fewer pregnancies, decreased maternal weight and advanced gestational week elevated the risk for OASI. With regard to parity, women with one previous delivery had approximately 1/3 of the risk for OASI compared to nulliparous women (OR = 0.3 (0.23–0.39), p < 0.001), and women with two previous deliveries had 1/3 of the risk compared to women with one previous delivery (OR = 0.35 (0.21–0.60), p < 0.001). Conclusion: Our machine learning-based model stratified births to high or low risk for OASI, making it an applicable tool for personalized decision-making upon admission to labor.

Original languageEnglish
Pages (from-to)2393-2399
Number of pages7
JournalInternational Urogynecology Journal
Volume32
Issue number9
DOIs
StatePublished - Sep 2021

Bibliographical note

Publisher Copyright:
© 2021, The International Urogynecological Association.

Keywords

  • Machine learning
  • Obstetric anal sphincter injury
  • Perineal laceration
  • Primiparity

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