Pre-miRNA expressing plasmid delivery for anti-cancer therapy

Elena Benisvy-Aharonovich; Ulyana Shimanovich; Noam Kronfeld; Nis Giladi; Ariel Bier; Gila Kazimirsky; Aharon Gedanken; Chaya Brodie

doi:10.1039/c3md00314k

Pre-miRNA expressing plasmid delivery for anti-cancer therapy

Elena Benisvy-Aharonovich, Ulyana Shimanovich, Noam Kronfeld, Nis Giladi, Ariel Bier, Gila Kazimirsky, Aharon Gedanken, Chaya Brodie

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

The preparation of Au NP complexes of the premiRNA-145/GFP expressing plasmid is reported; the latter is successfully delivered to glioma cells and the transcripted miRNA-145 efficiently decreases the expression of its target gene, connective tissue growth factor (CTGF).

Original language	English
Pages (from-to)	459-462
Number of pages	4
Journal	MedChemComm
Volume	5
Issue number	4
DOIs	https://doi.org/10.1039/c3md00314k
State	Published - Apr 2014

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title = "Pre-miRNA expressing plasmid delivery for anti-cancer therapy",

abstract = "The preparation of Au NP complexes of the premiRNA-145/GFP expressing plasmid is reported; the latter is successfully delivered to glioma cells and the transcripted miRNA-145 efficiently decreases the expression of its target gene, connective tissue growth factor (CTGF).",

author = "Elena Benisvy-Aharonovich and Ulyana Shimanovich and Noam Kronfeld and Nis Giladi and Ariel Bier and Gila Kazimirsky and Aharon Gedanken and Chaya Brodie",

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AU - Benisvy-Aharonovich, Elena

AU - Shimanovich, Ulyana

AU - Kronfeld, Noam

AU - Giladi, Nis

AU - Bier, Ariel

AU - Kazimirsky, Gila

AU - Gedanken, Aharon

AU - Brodie, Chaya

PY - 2014/4

Y1 - 2014/4

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DO - 10.1039/c3md00314k

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SN - 2040-2503

VL - 5

SP - 459

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JO - MedChemComm

JF - MedChemComm

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Pre-miRNA expressing plasmid delivery for anti-cancer therapy

Abstract

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