Potential for anatomic localization in colorectal cancer using the SCM test

O. Merimsky

Research output: Contribution to journalArticlepeer-review


We analysed a series of 81 colorectal cancer cases in which the SCM (structuredness of the cytoplasmic matrix) test had already been performed with a diagnostic sensitivity of 92% and a specificity of 92.6%, yielding positive and negative predictive values of 96.3% and 84.7% respectively. We subdivided this group of 81 patients by anatomic location of the malignancy. Although the resultant subgroups were admittedly small, we noted a tendency for the most prominent changes in observed and calculated polarization parameters to be associated with cecal cancers. This finding was of special interest because the cecum is the most inaccessible site for colonoscopy. Ongoing site-specific surveillance in SCM-tested cases of colorectal cancer is necessary to validate this result.

Original languageEnglish
Pages (from-to)1141-1143
Number of pages3
JournalOncology Reports
Issue number6
StatePublished - 1996
Externally publishedYes


  • colorectal cancer
  • cytoplasmic matrix


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