Posttransfusion Non‐A, Non‐B Hepatitis after Cardiac Surgery: A Prospective Study

Ran Tur‐Kaspa; Dov Victor Shimon; Meir Shalit; Ruth Adler; Shmuel Shraga; Noga Manny; Abraham Morag; Marcel Eliakim

doi:10.1111/j.1423-0410.1983.tb01919.x

Posttransfusion Non‐A, Non‐B Hepatitis after Cardiac Surgery: A Prospective Study

Ran Tur‐Kaspa, Dov Victor Shimon, Meir Shalit, Ruth Adler, Shmuel Shraga, Noga Manny, Abraham Morag, Marcel Eliakim

Departments of Medicine A

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Abstract

Abstract. In a prospective study of 50 recipients of HBsAg‐negative blood who had undergone cardiac surgery, 4 (8%) developed acute non‐A, non‐B hepatitis. The patients who developed hepatitis had received significantly more units of blood or blood products than the patients who had no hepatitis. The incubation period of the disease was 4–13 weeks, 3 patients were asymptomatic with peak alaminotransferase (ALT) levels of 320–497 U/l and 1 patient was jaundiced with a peak ALT of 3,400 U/l. 1 of the patients had high ALT levels after 21 weeks of observation, while 3 patients recovered after 7–10 weeks. It is concluded that non‐A, non‐B posttransfusion hepatitis in Israel is a medical problem similar to that in the USA and that the clinical picture of the disease varies from a mild asymptomatic to a symtomatic and protracted course.

Original language	English
Pages (from-to)	312-315
Number of pages	4
Journal	Vox Sanguinis
Volume	45
Issue number	4
DOIs	https://doi.org/10.1111/j.1423-0410.1983.tb01919.x
State	Published - Oct 1983
Externally published	Yes

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title = "Posttransfusion Non‐A, Non‐B Hepatitis after Cardiac Surgery: A Prospective Study",

abstract = "Abstract. In a prospective study of 50 recipients of HBsAg‐negative blood who had undergone cardiac surgery, 4 (8%) developed acute non‐A, non‐B hepatitis. The patients who developed hepatitis had received significantly more units of blood or blood products than the patients who had no hepatitis. The incubation period of the disease was 4–13 weeks, 3 patients were asymptomatic with peak alaminotransferase (ALT) levels of 320–497 U/l and 1 patient was jaundiced with a peak ALT of 3,400 U/l. 1 of the patients had high ALT levels after 21 weeks of observation, while 3 patients recovered after 7–10 weeks. It is concluded that non‐A, non‐B posttransfusion hepatitis in Israel is a medical problem similar to that in the USA and that the clinical picture of the disease varies from a mild asymptomatic to a symtomatic and protracted course.",

author = "Ran Tur‐Kaspa and Shimon, {Dov Victor} and Meir Shalit and Ruth Adler and Shmuel Shraga and Noga Manny and Abraham Morag and Marcel Eliakim",

year = "1983",

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doi = "10.1111/j.1423-0410.1983.tb01919.x",

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T2 - A Prospective Study

AU - Tur‐Kaspa, Ran

AU - Shimon, Dov Victor

AU - Shalit, Meir

AU - Adler, Ruth

AU - Shraga, Shmuel

AU - Manny, Noga

AU - Morag, Abraham

AU - Eliakim, Marcel

PY - 1983/10

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N2 - Abstract. In a prospective study of 50 recipients of HBsAg‐negative blood who had undergone cardiac surgery, 4 (8%) developed acute non‐A, non‐B hepatitis. The patients who developed hepatitis had received significantly more units of blood or blood products than the patients who had no hepatitis. The incubation period of the disease was 4–13 weeks, 3 patients were asymptomatic with peak alaminotransferase (ALT) levels of 320–497 U/l and 1 patient was jaundiced with a peak ALT of 3,400 U/l. 1 of the patients had high ALT levels after 21 weeks of observation, while 3 patients recovered after 7–10 weeks. It is concluded that non‐A, non‐B posttransfusion hepatitis in Israel is a medical problem similar to that in the USA and that the clinical picture of the disease varies from a mild asymptomatic to a symtomatic and protracted course.

AB - Abstract. In a prospective study of 50 recipients of HBsAg‐negative blood who had undergone cardiac surgery, 4 (8%) developed acute non‐A, non‐B hepatitis. The patients who developed hepatitis had received significantly more units of blood or blood products than the patients who had no hepatitis. The incubation period of the disease was 4–13 weeks, 3 patients were asymptomatic with peak alaminotransferase (ALT) levels of 320–497 U/l and 1 patient was jaundiced with a peak ALT of 3,400 U/l. 1 of the patients had high ALT levels after 21 weeks of observation, while 3 patients recovered after 7–10 weeks. It is concluded that non‐A, non‐B posttransfusion hepatitis in Israel is a medical problem similar to that in the USA and that the clinical picture of the disease varies from a mild asymptomatic to a symtomatic and protracted course.

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Posttransfusion Non‐A, Non‐B Hepatitis after Cardiac Surgery: A Prospective Study

Abstract

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