Abstract
Triacetonamine was used to synthesize a series of highly substituted 4-piperidones and 4-piperidols. The spatial configuration of these compounds was determined. The anionoid addition to the carbonyl group of these piperidones proceeds through highly stereoselective equatorial attack. The position of the chair-chair-twist conformational equilibrium was determined for the polysubstituted 4-piperidols.
| Original language | American English |
|---|---|
| Pages (from-to) | 421-429 |
| Journal | Bulletin of the Academy of Sciences of the USSR, Division of chemical science |
| Volume | 40 |
| Issue number | 2 |
| State | Published - 1991 |