Polysaccharide Based Nanoparticles

Wahid Khan; Ester Abtew; Sheela Modani; Abraham J. Domb

doi:10.1002/ijch.201800051

Polysaccharide Based Nanoparticles

Wahid Khan, Ester Abtew, Sheela Modani, Abraham J. Domb

Research output: Contribution to journal › Review article › peer-review

13 Scopus citations

Abstract

Nanoparticles made of biodegradable polymers have outstanding merits as a drug delivery system. Polysaccharide-based nanoparticles have been well explored because of their safety, stability, biocompatibility, biodegradability and hydrophilicity. The present review emphasizes the efforts articulated to improve polysaccharide-based nanoparticles as drug delivery tool for effective therapy and site-specific targeting of mainly anticancer agents. This review updates reports of recent research on polysaccharides-based systems particularly chitosan, alginate, cyclodextrins, hyaluronic acid, pullulan, dextran and their combinations with potential applications.

Original language	English
Pages (from-to)	1315-1329
Number of pages	15
Journal	Israel Journal of Chemistry
Volume	58
Issue number	12
DOIs	https://doi.org/10.1002/ijch.201800051
State	Published - Dec 2018
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim

Keywords

alginate
cancer
chitosan
cyclodextrin
drug delivery
nanoparticles
polysaccharides

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1002/ijch.201800051

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title = "Polysaccharide Based Nanoparticles",

abstract = "Nanoparticles made of biodegradable polymers have outstanding merits as a drug delivery system. Polysaccharide-based nanoparticles have been well explored because of their safety, stability, biocompatibility, biodegradability and hydrophilicity. The present review emphasizes the efforts articulated to improve polysaccharide-based nanoparticles as drug delivery tool for effective therapy and site-specific targeting of mainly anticancer agents. This review updates reports of recent research on polysaccharides-based systems particularly chitosan, alginate, cyclodextrins, hyaluronic acid, pullulan, dextran and their combinations with potential applications.",

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doi = "10.1002/ijch.201800051",

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AU - Khan, Wahid

AU - Abtew, Ester

AU - Modani, Sheela

AU - Domb, Abraham J.

PY - 2018/12

Y1 - 2018/12

N2 - Nanoparticles made of biodegradable polymers have outstanding merits as a drug delivery system. Polysaccharide-based nanoparticles have been well explored because of their safety, stability, biocompatibility, biodegradability and hydrophilicity. The present review emphasizes the efforts articulated to improve polysaccharide-based nanoparticles as drug delivery tool for effective therapy and site-specific targeting of mainly anticancer agents. This review updates reports of recent research on polysaccharides-based systems particularly chitosan, alginate, cyclodextrins, hyaluronic acid, pullulan, dextran and their combinations with potential applications.

AB - Nanoparticles made of biodegradable polymers have outstanding merits as a drug delivery system. Polysaccharide-based nanoparticles have been well explored because of their safety, stability, biocompatibility, biodegradability and hydrophilicity. The present review emphasizes the efforts articulated to improve polysaccharide-based nanoparticles as drug delivery tool for effective therapy and site-specific targeting of mainly anticancer agents. This review updates reports of recent research on polysaccharides-based systems particularly chitosan, alginate, cyclodextrins, hyaluronic acid, pullulan, dextran and their combinations with potential applications.

KW - alginate

KW - cancer

KW - chitosan

KW - cyclodextrin

KW - drug delivery

KW - nanoparticles

KW - polysaccharides

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EP - 1329

JO - Israel Journal of Chemistry

JF - Israel Journal of Chemistry

IS - 12

ER -

Polysaccharide Based Nanoparticles

Abstract

Bibliographical note

Keywords

UN SDGs

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