Platelet-associated antibodies mediate protective autoimmune response in schizophrenia

Michael S. Sinyakov, Bezalel Kessler, Leon Karp, Abraham Weizman, Abraham R. Kessler

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


The peripheral blood platelets of schizophrenic patients were isolated, and the level of the platelet-associated antibodies (SPAA) was correlated with the rating scores of discrete schizophrenic symptom clusters evaluated with the Brief Psychiatric Rating Scale. Irrespective of medication and gender, symptom-dependent correlations were established between the SPAA levels and the relevant psychometric scores. The results indicate a heterogeneous origin of schizophrenia and imply the involvement of an autoimmune arm as a predominantly protective immune response.

Original languageEnglish
Pages (from-to)41-46
Number of pages6
Issue number1
StatePublished - 2003


  • Autoimmunity
  • Platelet-associated antibodies
  • Schizophrenia
  • Symptom clusters


Dive into the research topics of 'Platelet-associated antibodies mediate protective autoimmune response in schizophrenia'. Together they form a unique fingerprint.

Cite this