Pericarditis and pericardial effusion in acute ST-elevation myocardial infarction in the thrombolytic era

Alp Aydinalp, Alice Wishniak, Lily Van Den Akker-Berman, Tsafrir Or, Nathan Roguin

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

Background: Myocardial infarction-associated pericarditis is a common cause of chest pain following MI, its frequency depending on how it is defined. Objectives: To investigate the incidence of acute pericarditis and pericardial effusion in the acute phase of ST-elevation MI treated with thrombolytic therapy. Methods: The study group comprised 159 consecutive patients fulfilling the criteria for acute MI who were admitted to our department during 18 months. Infarct-associated pericarditis was defined as the finding of a pericardial friction rub, a typical pleuropericardial pain, or both. All patients underwent physical examination of the cardiovascular system four times daily for 7 days, as well as daily electrocardiogram and echo Doppler examinations. Results: Fourteen patients (8.8%) developed a friction rub and 11 patients (6.9%) had a mild pericardial effusion. Six patients (4.0%) had both a friction rub and pericardial effusion. Two patients had a friction rub for more than 7 days. Pleuropericardial chest pain was present in 31 patients (19.5%) but only 7 of them had a friction rub. The in-hospital mortality rate was 1.3% and no mortality was observed in the acute pericarditis group. Conclusion: The incidence of signs associated with acute pericarditis was lower in MI patients treated with thrombolysis, compared with historical controls, when a friction rub and/or pericardial effusion was present. There was no significant reduction in the incidence of pleuropericardial chest pain.

Original languageEnglish
Pages (from-to)181-183
Number of pages3
JournalIsrael Medical Association Journal
Volume4
Issue number3
StatePublished - Mar 2002
Externally publishedYes

Keywords

  • Acute ST-elevation
  • Myocardial infarction
  • Pericardial effusion
  • Pericarditis
  • Thrombolysis

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