Peptides form stereoselective complexes with chiral polymers

Joram Slager, Yachin Cohen, Rafail Khalfin, Yeshayahu Talmon, Abraham J. Domb

Research output: Contribution to journalArticlepeer-review

31 Scopus citations


Reversible stereoselective complexes between L-peptides and enantioselective D-polysters were discovered. The spontaneously formed complexes obtained as uniform microparticles of 2-5μm in size showed controlled release of the interlocked peptides. The stereoselective complexation occurred only with D-PLA, not with L-PLA or racemic DL-PLA as shown by SAXS studies.

Original languageEnglish
Pages (from-to)2999-3000
Number of pages2
Issue number9
StatePublished - 6 May 2003
Externally publishedYes


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