Abstract
Several peptides are now known to affect thermoregulation. These include beta-endorphin, bombesin, MIF-I, alpha-MSH, neurotensin, TRH, and DSIP. Some of these have been found to interact with the thermal effects of d-amphetamine, a drug with well established actions on thermoregulation. The effects of morphine on body temperature provide some notable comparisons with beta-endorphin, as do the similarities between the effects of naloxone and MIF-I. In general, it seems that two of the major variables which interact and modify the thermal effects of peptides are ambient temperature and route of administration.
Original language | English |
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Pages (from-to) | 459-471 |
Number of pages | 13 |
Journal | Neuroscience and Biobehavioral Reviews |
Volume | 4 |
Issue number | 4 |
DOIs | |
State | Published - 1980 |
Externally published | Yes |
Bibliographical note
Funding Information:Supported in part by the Medical Research Service of the Veterans Administration, NIH (NS 07664), and The American Parkinson Disease Foundation.
Funding
Supported in part by the Medical Research Service of the Veterans Administration, NIH (NS 07664), and The American Parkinson Disease Foundation.
Funders | Funder number |
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Medical Research Service of the Veterans Administration | |
National Institutes of Health | NS 07664 |
American Parkinson's Disease Foundation |
Keywords
- Alpha-MSH
- Ambient temperature
- Beta-endorphin
- Bombesin
- DSIP
- Drug interaction
- Hyperthermia
- Hypothermia
- MIF-I
- Morphine
- Naloxone
- Neurotensin
- Peptides
- TRH
- Thermoregulation
- d-Amphetamine