Abstract
Several peptides are now known to affect thermoregulation. These include beta-endorphin, bombesin, MIF-I, alpha-MSH, neurotensin, TRH, and DSIP. Some of these have been found to interact with the thermal effects of d-amphetamine, a drug with well established actions on thermoregulation. The effects of morphine on body temperature provide some notable comparisons with beta-endorphin, as do the similarities between the effects of naloxone and MIF-I. In general, it seems that two of the major variables which interact and modify the thermal effects of peptides are ambient temperature and route of administration.
| Original language | English |
|---|---|
| Pages (from-to) | 459-471 |
| Number of pages | 13 |
| Journal | Neuroscience and Biobehavioral Reviews |
| Volume | 4 |
| Issue number | 4 |
| DOIs | |
| State | Published - 1980 |
| Externally published | Yes |
Bibliographical note
Funding Information:Supported in part by the Medical Research Service of the Veterans Administration, NIH (NS 07664), and The American Parkinson Disease Foundation.
Keywords
- Alpha-MSH
- Ambient temperature
- Beta-endorphin
- Bombesin
- DSIP
- Drug interaction
- Hyperthermia
- Hypothermia
- MIF-I
- Morphine
- Naloxone
- Neurotensin
- Peptides
- TRH
- Thermoregulation
- d-Amphetamine