Peptides and thermoregulation

Shlomo Yehuda, Abba J. Kastin

Research output: Contribution to journalArticlepeer-review

71 Scopus citations


Several peptides are now known to affect thermoregulation. These include beta-endorphin, bombesin, MIF-I, alpha-MSH, neurotensin, TRH, and DSIP. Some of these have been found to interact with the thermal effects of d-amphetamine, a drug with well established actions on thermoregulation. The effects of morphine on body temperature provide some notable comparisons with beta-endorphin, as do the similarities between the effects of naloxone and MIF-I. In general, it seems that two of the major variables which interact and modify the thermal effects of peptides are ambient temperature and route of administration.

Original languageEnglish
Pages (from-to)459-471
Number of pages13
JournalNeuroscience and Biobehavioral Reviews
Issue number4
StatePublished - 1980
Externally publishedYes

Bibliographical note

Funding Information:
Supported in part by the Medical Research Service of the Veterans Administration, NIH (NS 07664), and The American Parkinson Disease Foundation.


  • Alpha-MSH
  • Ambient temperature
  • Beta-endorphin
  • Bombesin
  • DSIP
  • Drug interaction
  • Hyperthermia
  • Hypothermia
  • MIF-I
  • Morphine
  • Naloxone
  • Neurotensin
  • Peptides
  • TRH
  • Thermoregulation
  • d-Amphetamine


Dive into the research topics of 'Peptides and thermoregulation'. Together they form a unique fingerprint.

Cite this