TY - JOUR
T1 - Parents' attitudes toward methylphenidate using n-of-1 trial
T2 - A pilot study
AU - Taragin, Dorit
AU - Berman, Suzana
AU - Zelnik, Nathanel
AU - Karni, Avi
AU - Tirosh, Emanuel
PY - 2013/6
Y1 - 2013/6
N2 - To compare parents' attitudes toward methylphenidate treatment in children with attention deficit hyperactivity disorder employing two approaches: (1) a 2-week double-blind placebo-drug trial (n-of-1 trial), (2) a traditional prescription approach. The study group (N-50) and a comparison group (N-45) were recruited. The Abbreviated Acceptability Rating Profile was administered prior to and following the pediatricians' consultation, and in 2, 4, and 8 weeks after prescription. Complete data set was available for 21 children in each group. While initial attitudes were similar, a significantly more favorable attitude following the performance of an n-of-1 trial and throughout the follow-up in the study group only was noted. Adherence was significantly correlated with attitude score in the study group only. An individual n-of-1 trial with methylphenidate appears to positively affect parents' attitudes toward drug treatment and may also help adherence with this treatment.
AB - To compare parents' attitudes toward methylphenidate treatment in children with attention deficit hyperactivity disorder employing two approaches: (1) a 2-week double-blind placebo-drug trial (n-of-1 trial), (2) a traditional prescription approach. The study group (N-50) and a comparison group (N-45) were recruited. The Abbreviated Acceptability Rating Profile was administered prior to and following the pediatricians' consultation, and in 2, 4, and 8 weeks after prescription. Complete data set was available for 21 children in each group. While initial attitudes were similar, a significantly more favorable attitude following the performance of an n-of-1 trial and throughout the follow-up in the study group only was noted. Adherence was significantly correlated with attitude score in the study group only. An individual n-of-1 trial with methylphenidate appears to positively affect parents' attitudes toward drug treatment and may also help adherence with this treatment.
KW - Attention deficit hyperactivity disorder (ADHD)
KW - Methylphenidate
KW - Parents' attitudes
KW - n-of-1 trial
UR - https://www.scopus.com/pages/publications/84877354603
U2 - 10.1007/s12402-012-0099-x
DO - 10.1007/s12402-012-0099-x
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C2 - 23242806
AN - SCOPUS:84877354603
SN - 1866-6116
VL - 5
SP - 105
EP - 109
JO - ADHD Attention Deficit and Hyperactivity Disorders
JF - ADHD Attention Deficit and Hyperactivity Disorders
IS - 2
ER -
