Nano palladium decorated multi walled carbon nanotubes (PdNP:MWCNT) have been synthesized in a simple single step, followed by their characterization using field emission scanning electron microscopy, energy dispersion X-ray spectroscopy, X-ray diffraction, electrochemical impedance spectroscopy and voltammetry. The PdNP:MWCNT was then used for the surface modification of glassy carbon electrode (GCE) and applied for the electrochemical analysis of 5-hydroxytryptophan (5-HTP), a serotonin precursor. A significant increment in peak current response was observed and peak potential also shifted towards less positive potentials indicating the facilitated oxidation process at PdNP:MWCNT/GCE. The quantitative determination of 5-HTP was carried out by using square wave voltammetry and the anodic peak current was found to increase with increasing 5-HTP concentration in the linear range of 2–400 μM with a sensitivity and limit of detection of 0.2122 μA/μM and 77 nM respectively. The fabricated sensor further displayed excellent selectivity for 5-HTP in presence of major interfering biomolecules in the urine with excellent recovery.
Bibliographical noteFunding Information:
Authors (Neeraj Kumar and Rosy) are thankful to the Ministry of Human Resources, New Delhi for awarding Junior Research Fellowship and Senior Research Fellowship respectively.
Rajendra N Goyal obtained Ph.D. in 1975 from Roorkee University and D.Sc. from Agra University, India in 1991. He worked as postdoctoral fellow at University of Oklahoma, Norman, USA during 1979–1982 and again during 1989–1991. He was British Council fellow at University of Loughborough, UK during 1979 and was visiting professor at Kyoto University, Japan during 2007. He was JSPS invitation research fellowship recipient in years 2003 and 2014. Presently Dr. Goyal is working as Professor in Department of Chemistry, I.I.T. Roorkee, Roorkee, India. His current research area includes molecular electrochemistry, electrochemistry at nano-material modified electrodes and sensors and biosensors for doping agents
© 2016 Elsevier B.V.
- Multi-wall carbon tube
- Palladium nano particles