Abstract
Abstract
Reports an error in "Oxytocin and behavior: Evidence for effects in the brain" by Francis L. Stevens, Omri Wiesman, Ruth Feldman, Robin A. Hurley and Katherine H. Taber (The Journal of Neuropsychiatry and Clinical Neurosciences, 2013[Spr], Vol 25[2], 96-102). In the original article, the name of author Omri Weisman was misspelled. (The following abstract of the original article appeared in record 2013-18144-001). This article testifies behavior of oxytocin and its effects in the brain. Oxytocin (OT) is a nine amino acid peptide, synthesized primarily in the supraoptic and paraventricular nuclei (SON and PVN) of the hypothalamus. An intriguing aspect of the OT system in the CNS is the presence of areas with substantial OT receptor binding but low levels of fibers staining for OT, such as the substantia nigra pars compacta. OT, like other neuropeptides, is stored in large dense-core vesicles which are found in and can release OT from multiple locations. Some studies have found that peripheral OT levels are significantly increased in the early stages of romantic attachment and that OT levels correlated with positive behaviors. Functional neuroimaging (primarily fMRI) has begun to shed light on the brain areas affected by intranasal administration of OT. Altered amygdala reactivity to emotional stimuli has been the most common findings. At present, there are multiple theories for OT's effect with varying implications for use of OT as a therapeutic agent
Reports an error in "Oxytocin and behavior: Evidence for effects in the brain" by Francis L. Stevens, Omri Wiesman, Ruth Feldman, Robin A. Hurley and Katherine H. Taber (The Journal of Neuropsychiatry and Clinical Neurosciences, 2013[Spr], Vol 25[2], 96-102). In the original article, the name of author Omri Weisman was misspelled. (The following abstract of the original article appeared in record 2013-18144-001). This article testifies behavior of oxytocin and its effects in the brain. Oxytocin (OT) is a nine amino acid peptide, synthesized primarily in the supraoptic and paraventricular nuclei (SON and PVN) of the hypothalamus. An intriguing aspect of the OT system in the CNS is the presence of areas with substantial OT receptor binding but low levels of fibers staining for OT, such as the substantia nigra pars compacta. OT, like other neuropeptides, is stored in large dense-core vesicles which are found in and can release OT from multiple locations. Some studies have found that peripheral OT levels are significantly increased in the early stages of romantic attachment and that OT levels correlated with positive behaviors. Functional neuroimaging (primarily fMRI) has begun to shed light on the brain areas affected by intranasal administration of OT. Altered amygdala reactivity to emotional stimuli has been the most common findings. At present, there are multiple theories for OT's effect with varying implications for use of OT as a therapeutic agent
| Original language | American English |
|---|---|
| Pages (from-to) | 249 |
| Number of pages | 1 |
| Journal | Journal of Neuropsychiatry and Clinical Neurosciences |
| Volume | 25 |
| Issue number | 3 |
| DOIs |
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| State | Published - 2013 |