TY - JOUR
T1 - Oxygen - a limiting factor for brain recovery
AU - Hadanny, Amir
AU - Efrati, Shai
N1 - Publisher Copyright:
© 2015 Hadanny and Efrati.
PY - 2015/9/1
Y1 - 2015/9/1
N2 - Effective brain metabolism is highly dependent on a narrow therapeutic window of oxygen. In major insults to the brain (e.g., intracerebral hemorrhage), a slight decrease in oxygen supply, as occurs in a hypobaric environment at high altitude, has devastating effects on the injured brain tissue. Conversely, increasing brain oxygenation, by the use of hyperbaric oxygen therapy, can improve brain metabolism and its dependent regenerative processes.
AB - Effective brain metabolism is highly dependent on a narrow therapeutic window of oxygen. In major insults to the brain (e.g., intracerebral hemorrhage), a slight decrease in oxygen supply, as occurs in a hypobaric environment at high altitude, has devastating effects on the injured brain tissue. Conversely, increasing brain oxygenation, by the use of hyperbaric oxygen therapy, can improve brain metabolism and its dependent regenerative processes.
UR - http://www.scopus.com/inward/record.url?scp=84940552366&partnerID=8YFLogxK
U2 - 10.1186/s13054-015-1034-2
DO - 10.1186/s13054-015-1034-2
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C2 - 26329929
AN - SCOPUS:84940552366
SN - 1364-8535
VL - 19
JO - Critical Care
JF - Critical Care
IS - 1
M1 - 307
ER -