TY - GEN
T1 - Oxidative stress on Ti6Al4V alloy reduces inflammatory response of endothelial cells
AU - Tsaryk, Roman
AU - Peters, Kirsten
AU - Unger, Ronald E.
AU - Scharnweber, Dieter
AU - Kirkpatrick, C. James
PY - 2008
Y1 - 2008
N2 - In this study we have demonstrated that endothelial cells grown on Ti6Al4V alloy show decreased ability to react to pro-inflammatory stimuli TNF-α and LPS than the cells grown on PS. This is most probably due to increased oxidative stress induced by Ti6Al4V alloy. This decreased pro-inflammatory capacity could have an impact on the function of endothelial cells in wound healing and determine the success of the implant integration.
AB - In this study we have demonstrated that endothelial cells grown on Ti6Al4V alloy show decreased ability to react to pro-inflammatory stimuli TNF-α and LPS than the cells grown on PS. This is most probably due to increased oxidative stress induced by Ti6Al4V alloy. This decreased pro-inflammatory capacity could have an impact on the function of endothelial cells in wound healing and determine the success of the implant integration.
UR - http://www.scopus.com/inward/record.url?scp=84869013080&partnerID=8YFLogxK
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AN - SCOPUS:84869013080
SN - 9781615670802
T3 - 8th World Biomaterials Congress 2008
SP - 1598
BT - 8th World Biomaterials Congress 2008
T2 - 8th World Biomaterials Congress 2008, WBC 2008
Y2 - 28 May 2008 through 1 June 2008
ER -