Abstract
Stereoselective formation of six-membered carbacycles with biological and pharmaceutical relevance is one of the prime research areas in modern organic synthesis. Various innovative synthetic protocols involving asymmetric C-C bond forming reactions have been developed and exploited widely. The present review attempts to elaborate the original contributions and recent advancements made in this field for the stereoselective synthesis of a diverse array of asymmetric sixmembered carbacyclic compounds employing very simple and/or advanced organocatalytic domino reactions.
| Original language | English |
|---|---|
| Pages (from-to) | 2842-2856 |
| Number of pages | 15 |
| Journal | Current Organic Chemistry |
| Volume | 18 |
| Issue number | 22 |
| DOIs | |
| State | Published - 1 Jan 2014 |
| Externally published | Yes |
Bibliographical note
Publisher Copyright:© 2014 Bentham Science Publishers.
Keywords
- C-C bond formation
- Carbacycles
- Cascade
- Enantioselective
- Michael reaction
- Organocatalysis
- Tandem
- domino reaction