Optimization of 1,2,4-Triazole-Based p97 Inhibitors for the Treatment of Cancer

Keyphrases

• Cancer Treatment 100%
• P97 Inhibitor 100%
• Allosteric Inhibitor 100%
• 1,2,4-triazole 100%
• Master Regulator 50%
• Cell-based 50%
• Apoptosis 50%
• Cancer Therapy 50%
• Cleaved caspase-3 50%
• Replacement Strategy 50%
• Benzene 50%
• Protein Homeostasis 50%
• AAA+ ATPase 50%
• Acetylene 50%
• NMS-873 50%
• Pharmacodynamic Assay 50%
• Cellular Pharmacokinetics 50%
• Eutomer 50%
• Valosin-containing Protein 50%
• Isosteric Replacement 50%
• Distomer 50%
• Ubiquitin-like Protein 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Malignant Neoplasm 100%
• Triazole 100%
• Pharmacodynamics 50%
• Biological Marker 50%
• Adenosine Triphosphatase 50%
• Ubiquitinated Protein 50%
• Acetylene 50%
• Growth Arrest and DNA Damage Inducible Protein 153 50%
• Valosin Containing Protein 50%
• Caspase 3 50%
• Benzene 50%

Biochemistry, Genetics and Molecular Biology

• P97 100%
• Benzene 25%
• AAA+ 25%
• Pharmacodynamics 25%
• Protein Homeostasis 25%
• DNA Damage-Inducible Transcript 3 25%
• ATPase 25%
• Caspase 3 25%
• Valosin-Containing Protein 25%
• Programmed Cell Death 25%