Optical detection of hidden tumors

Ran Vered; Shlomo Havlin; Haim Taitelbaum

doi:10.1117/12.210035

Optical detection of hidden tumors

Ran Vered, Shlomo Havlin, Haim Taitelbaum

Department of Physics

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

5 Scopus citations

Abstract

We study the optical detection of absorptive tumors in turbid tissues, using a random-walk model to describe the migration of photons in the tissue. We consider time-resolved transillumination measurements in slab-like tissues, and calculate the tranmsmitted intensity with and without the inclusion. The ratio of these quantities, defined as the measure of the detectability, is studied as a function of the inclusion size and absorption coefficient. The detectability is found to depend only on the difference between the absorptivities of the abnormality and the surrounding tissue. The nonmonotonic behavior in time of this ratio corresponds to the three different types of photon trajectories in the tissue, and its extremum points provide information which can be used to determine the optimal time window for best detection.

Original language	English
Title of host publication	Optical Tomography, Photon Migration, and Spectroscopy of Tissue and Model Media
Subtitle of host publication	Theory, Human Studies, and Instrumentation
Editors	Britton Chance, Robert R. Alfano
Publisher	SPIE
Pages	851-858
Number of pages	8
ISBN (Electronic)	9780819417367
DOIs	https://doi.org/10.1117/12.210035
State	Published - 30 May 1995
Event	Optical Tomography, Photon Migration, and Spectroscopy of Tissue and Model Media: Theory, Human Studies, and Instrumentation - San Jose, United States Duration: 1 Feb 1995 → 28 Feb 1995

Publication series

Name	Proceedings of SPIE - The International Society for Optical Engineering
Volume	2389
ISSN (Print)	0277-786X
ISSN (Electronic)	1996-756X

Conference

Conference	Optical Tomography, Photon Migration, and Spectroscopy of Tissue and Model Media: Theory, Human Studies, and Instrumentation
Country/Territory	United States
City	San Jose
Period	1/02/95 → 28/02/95

Bibliographical note

Publisher Copyright:
© 2018 SPIE.

Keywords

Detectability
Exact Enumeration
Random-Walk
Transillumination
Tumor

Access to Document

10.1117/12.210035

Cite this

Vered, R., Havlin, S., & Taitelbaum, H. (1995). Optical detection of hidden tumors. In B. Chance, & R. R. Alfano (Eds.), Optical Tomography, Photon Migration, and Spectroscopy of Tissue and Model Media: Theory, Human Studies, and Instrumentation (pp. 851-858). (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 2389). SPIE. https://doi.org/10.1117/12.210035

@inproceedings{84abe8c6395f457d80665e9811a5ed4a,

title = "Optical detection of hidden tumors",

abstract = "We study the optical detection of absorptive tumors in turbid tissues, using a random-walk model to describe the migration of photons in the tissue. We consider time-resolved transillumination measurements in slab-like tissues, and calculate the tranmsmitted intensity with and without the inclusion. The ratio of these quantities, defined as the measure of the detectability, is studied as a function of the inclusion size and absorption coefficient. The detectability is found to depend only on the difference between the absorptivities of the abnormality and the surrounding tissue. The nonmonotonic behavior in time of this ratio corresponds to the three different types of photon trajectories in the tissue, and its extremum points provide information which can be used to determine the optimal time window for best detection.",

keywords = "Detectability, Exact Enumeration, Random-Walk, Transillumination, Tumor",

author = "Ran Vered and Shlomo Havlin and Haim Taitelbaum",

note = "Publisher Copyright: {\textcopyright} 2018 SPIE.; Optical Tomography, Photon Migration, and Spectroscopy of Tissue and Model Media: Theory, Human Studies, and Instrumentation ; Conference date: 01-02-1995 Through 28-02-1995",

year = "1995",

month = may,

day = "30",

doi = "10.1117/12.210035",

language = "אנגלית",

series = "Proceedings of SPIE - The International Society for Optical Engineering",

publisher = "SPIE",

pages = "851--858",

editor = "Britton Chance and Alfano, {Robert R.}",

booktitle = "Optical Tomography, Photon Migration, and Spectroscopy of Tissue and Model Media",

address = "ארצות הברית",

}

Vered, R, Havlin, S & Taitelbaum, H 1995, Optical detection of hidden tumors. in B Chance & RR Alfano (eds), Optical Tomography, Photon Migration, and Spectroscopy of Tissue and Model Media: Theory, Human Studies, and Instrumentation. Proceedings of SPIE - The International Society for Optical Engineering, vol. 2389, SPIE, pp. 851-858, Optical Tomography, Photon Migration, and Spectroscopy of Tissue and Model Media: Theory, Human Studies, and Instrumentation, San Jose, United States, 1/02/95. https://doi.org/10.1117/12.210035

Optical detection of hidden tumors. / Vered, Ran; Havlin, Shlomo; Taitelbaum, Haim.
Optical Tomography, Photon Migration, and Spectroscopy of Tissue and Model Media: Theory, Human Studies, and Instrumentation. ed. / Britton Chance; Robert R. Alfano. SPIE, 1995. p. 851-858 (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 2389).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Optical detection of hidden tumors

AU - Vered, Ran

AU - Havlin, Shlomo

AU - Taitelbaum, Haim

PY - 1995/5/30

Y1 - 1995/5/30

N2 - We study the optical detection of absorptive tumors in turbid tissues, using a random-walk model to describe the migration of photons in the tissue. We consider time-resolved transillumination measurements in slab-like tissues, and calculate the tranmsmitted intensity with and without the inclusion. The ratio of these quantities, defined as the measure of the detectability, is studied as a function of the inclusion size and absorption coefficient. The detectability is found to depend only on the difference between the absorptivities of the abnormality and the surrounding tissue. The nonmonotonic behavior in time of this ratio corresponds to the three different types of photon trajectories in the tissue, and its extremum points provide information which can be used to determine the optimal time window for best detection.

AB - We study the optical detection of absorptive tumors in turbid tissues, using a random-walk model to describe the migration of photons in the tissue. We consider time-resolved transillumination measurements in slab-like tissues, and calculate the tranmsmitted intensity with and without the inclusion. The ratio of these quantities, defined as the measure of the detectability, is studied as a function of the inclusion size and absorption coefficient. The detectability is found to depend only on the difference between the absorptivities of the abnormality and the surrounding tissue. The nonmonotonic behavior in time of this ratio corresponds to the three different types of photon trajectories in the tissue, and its extremum points provide information which can be used to determine the optimal time window for best detection.

KW - Detectability

KW - Exact Enumeration

KW - Random-Walk

KW - Transillumination

KW - Tumor

UR - http://www.scopus.com/inward/record.url?scp=54849409255&partnerID=8YFLogxK

U2 - 10.1117/12.210035

DO - 10.1117/12.210035

M3 - ???researchoutput.researchoutputtypes.contributiontobookanthology.conference???

AN - SCOPUS:54849409255

T3 - Proceedings of SPIE - The International Society for Optical Engineering

SP - 851

EP - 858

BT - Optical Tomography, Photon Migration, and Spectroscopy of Tissue and Model Media

A2 - Chance, Britton

A2 - Alfano, Robert R.

PB - SPIE

T2 - Optical Tomography, Photon Migration, and Spectroscopy of Tissue and Model Media: Theory, Human Studies, and Instrumentation

Y2 - 1 February 1995 through 28 February 1995

ER -

Optical detection of hidden tumors

Abstract

Publication series

Conference

Bibliographical note

Keywords

Access to Document

Other files and links

Fingerprint

Cite this