On the reactions of Cu(II/I)ATP complexes with methyl radicals

Ana Lerner; Dan Meyerstein; Alex Blahman; Magal Saphier; Guy Yardeni; Eric Maimon; Haya Kornweitz; Israel Zilbermann

doi:10.1016/j.jinorgbio.2022.111883

On the reactions of Cu(II/I)ATP complexes with methyl radicals

Ana Lerner
, Dan Meyerstein
, Alex Blahman
, Magal Saphier
, Guy Yardeni
, Eric Maimon
, Haya Kornweitz
, Israel Zilbermann

Ben-Gurion University of the Negev
Israel Atomic Energy Commission
Ariel University
Nuclear Research Center-Negev

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

The Cu^I/IIATP react with methyl radicals to form methane and methanol, where Cu^IATP reacts with ^•CH₃ in a process that is surprisingly slow. The low-rate constant of this process is attributed to the significant rearrangement of the chelating ligand required for the transient's formation. These results were corroborated by DFT calculations of the relevant compounds.

Original language	English
Article number	111883
Journal	Journal of Inorganic Biochemistry
Volume	234
DOIs	https://doi.org/10.1016/j.jinorgbio.2022.111883
State	Published - Sep 2022
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2022

Keywords

Adenosine triphosphate
Copper complexes
DFT
Radicals
Radiolysis
Reaction mechanisms

Access to Document

10.1016/j.jinorgbio.2022.111883

Cite this

@article{c3037983046141f783a4a8f8febcc470,

title = "On the reactions of Cu(II/I)ATP complexes with methyl radicals",

abstract = "The CuI/IIATP react with methyl radicals to form methane and methanol, where CuIATP reacts with •CH3 in a process that is surprisingly slow. The low-rate constant of this process is attributed to the significant rearrangement of the chelating ligand required for the transient's formation. These results were corroborated by DFT calculations of the relevant compounds.",

keywords = "Adenosine triphosphate, Copper complexes, DFT, Radicals, Radiolysis, Reaction mechanisms",

author = "Ana Lerner and Dan Meyerstein and Alex Blahman and Magal Saphier and Guy Yardeni and Eric Maimon and Haya Kornweitz and Israel Zilbermann",

note = "Publisher Copyright: {\textcopyright} 2022",

year = "2022",

month = sep,

doi = "10.1016/j.jinorgbio.2022.111883",

language = "אנגלית",

volume = "234",

journal = "Journal of Inorganic Biochemistry",

issn = "0162-0134",

publisher = "Elsevier",

}

TY - JOUR

T1 - On the reactions of Cu(II/I)ATP complexes with methyl radicals

AU - Lerner, Ana

AU - Meyerstein, Dan

AU - Blahman, Alex

AU - Saphier, Magal

AU - Yardeni, Guy

AU - Maimon, Eric

AU - Kornweitz, Haya

AU - Zilbermann, Israel

PY - 2022/9

Y1 - 2022/9

N2 - The CuI/IIATP react with methyl radicals to form methane and methanol, where CuIATP reacts with •CH3 in a process that is surprisingly slow. The low-rate constant of this process is attributed to the significant rearrangement of the chelating ligand required for the transient's formation. These results were corroborated by DFT calculations of the relevant compounds.

AB - The CuI/IIATP react with methyl radicals to form methane and methanol, where CuIATP reacts with •CH3 in a process that is surprisingly slow. The low-rate constant of this process is attributed to the significant rearrangement of the chelating ligand required for the transient's formation. These results were corroborated by DFT calculations of the relevant compounds.

KW - Adenosine triphosphate

KW - Copper complexes

KW - DFT

KW - Radicals

KW - Radiolysis

KW - Reaction mechanisms

UR - https://www.scopus.com/pages/publications/85132514003

U2 - 10.1016/j.jinorgbio.2022.111883

DO - 10.1016/j.jinorgbio.2022.111883

M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???

C2 - 35717883

AN - SCOPUS:85132514003

SN - 0162-0134

VL - 234

JO - Journal of Inorganic Biochemistry

JF - Journal of Inorganic Biochemistry

M1 - 111883

ER -

On the reactions of Cu(II/I)ATP complexes with methyl radicals

Abstract

Bibliographical note

Keywords

Access to Document

Other files and links

Fingerprint

Cite this