Omicron BA.2.75 variant is efficiently neutralised following BA.1 and BA.5 breakthrough infection in vaccinated individuals, Israel, June to September 2022

Nofar Atari, Limor Kliker, Neta Zuckerman, Bayan Abd Elkader, Yael Weiss-Ottolenghi, Ella Mendelson, Yitshak Kreiss, Gili Regev-Yochay, Michal Mandelboim

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

We evaluated neutralising antibody titres against wild type (WT) SARS-CoV-2 and four Omicron variants (BA.1, BA.2, BA.5 and BA.2.75) in fully vaccinated (three doses of Comirnaty vaccine) healthcare workers (HCW) in Israel who had breakthrough BA.1/BA5 infections. Omicron breakthrough infections in vaccinated individuals resulted in increased neutralising antibodies against the WT and Omicron variants compared with vaccinated uninfected HCW. HCW who recovered from BA.1 or BA.5 infections showed similar neutralising antibodies levels against BA.2.75.

Original languageEnglish
JournalEurosurveillance
Volume27
Issue number44
DOIs
StatePublished - 3 Nov 2022
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2022 European Centre for Disease Prevention and Control (ECDC). All rights reserved.

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