Nutrition and physical activity and chronic disease prevention: Research strategies and recommendations

Ross L. Prentice, Walter C. Willet, Peter Greenwald, David Alberts, Leslie Bernstein, Norman F. Boyd, Tim Byers, Steven K. Clinton, Gary Fraser, Laurence Freedman, David Hunter, Victor Kipnis, Laurence N. Kolonel, Bruce S. Kristal, Alan Kristal, Johanna W. Lampe, Anne McTiernan, John Milner, Ruth E. Patterson, John D. PotterElio Riboli, Arthur Schatzkin, Allison Yates, Elizabeth Yetley

Research output: Contribution to journalArticlepeer-review

72 Scopus citations


A shortage of credible information exists on practical dietary and physical activity patterns that have potential to reverse the national obesity epidemic and reduce the risk of major cancers and other chronic diseases. Securing such information is a challenging task, and there is considerable diversity of opinion concerning related research designs and priorities. Here, we put forward some perspectives on useful methodology and infrastructure developments for progress in this important area, and we list high-priority research topics in the areas of 1) assessment of nutrient intake and energy expenditure; 2) development of intermediate outcome biomarkers; 3) enhancement of cohort and cross-cultural studies; and 4) criteria for and development of full-scale nutrition and physical activity intervention trials.

Original languageEnglish
Pages (from-to)1276-1287
Number of pages12
JournalJournal of the National Cancer Institute
Issue number17
StatePublished - 1 Sep 2004


FundersFunder number
National Cancer InstituteP01CA053996


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