Nucleoside - 2′,3′/3′,5′-bis(thio)phosphate analogues are promising antioxidants acting mainly via Cu⁺/Fe ²⁺ ion chelation

Keyphrases

• Cu + 100%
• Nucleosides 100%
• Antioxidant 100%
• Fe2+ 100%
• Phosphate Analog 100%
• Thio 100%
• Ion Chelation 100%
• IC50 66%
• Hydrogen Peroxide 33%
• Bisphosphonates 33%
• 5-bisphosphate 33%
• Fenton Reaction 33%
• Chelator 33%
• 2′-deoxyadenosine 33%
• Ethylenediaminetetraacetic Acid 33%
• Adenosine 5′-monophosphate 33%
• Electron Paramagnetic Resonance 16%
• Titration 16%
• Radical Anions 16%
• 1H nuclear Magnetic Resonance (1H NMR) 16%
• Biocompatibility 16%
• Reaction Conditions 16%
• Adenosine Diphosphate 16%
• Adenosine 16%
• 31P NMR 16%
• Metal Chelator 16%
• Nitrogen Atom 16%
• Antioxidant Activity 16%
• Phosphate Group 16%
• Guanine 16%
• Water-soluble Antioxidants 16%
• OH Radical 16%
• Radical Scavenger 16%
• Trolox 16%
• Radical Production 16%
• Assay Data 16%
• H2O2 Decomposition 16%
• 2,2′-Azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) 16%
• Guanosine-5′-monophosphate 16%

Pharmacology, Toxicology and Pharmaceutical Science

• Cuprous Ion 100%
• Antioxidant 100%
• Nucleoside 100%
• IC50 66%
• Ferrous Ion 50%
• Hydrogen Peroxide 50%
• Chelating Agent 50%
• Adenosine 50%
• Ethylenediaminetetraacetic Acid 33%
• Cordycepin 33%
• Fenton Reaction 33%
• Antioxidant Capacity 16%
• Sulfonic Acid 16%
• Guanosine Phosphate 16%
• Metal Ion 16%
• Adenine 16%
• Phosphorus 31 16%
• Scavenger 16%
• Trolox C 16%
• Adenosine Diphosphate 16%
• Guanine 16%

Biochemistry, Genetics and Molecular Biology

• Chelation 100%
• IC50 100%
• Nucleoside 100%
• Adenosine 75%
• Hydrogen Peroxide 75%
• Fenton Reaction 50%
• Deoxyadenosine 50%
• Electron Paramagnetic Resonance 25%
• Alpha Oxidation 25%
• Adenine 25%
• Guanine 25%
• Trolox 25%
• Antioxidant Activity 25%
• Scavenger 25%
• Adenosine Diphosphate 25%
• Sulfonic Acid 25%
• Guanosine Monophosphate 25%