Novel vapor phase biodegradable coatings for controlled drug delivery systems

Arul Chakkaravarthi Arjunan, Sushant Gupta, Rajiv K. Singh, Deepika Singh, Jeff Opalko

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Scopus citations


The synthesis of nano-functionalized drug particles or drug particles with nanoscale biodegradable polymeric coatings has wider ranging applications in sustained release drug delivery systems. An important area of application includes delivery of drugs, such as proteins, peptides, and glucocorticoids via the inhalation process. The advantages of this method include, rapid absorption by the body and lack of metabolic degradation effects which is typically by some drugs during oral delivery. Here we discuss the novel pulsed laser and pulsed electron method to synthesize nanoscale biodegradable coatings of poly lactic acid (PLA). A unique method for depositing the PLA films, pulsed electron beam deposition (PED) was used to deposit the films. This technique was tried done to overcome the difficulties like low absorption co-efficient of UViaser. Method proved to be promising for producing smooth films and offers a better thickness control of the deposition. The roughness and other morphological characteristics of PED deposited films were superior over the conventional laser ablated films.

Original languageEnglish
Title of host publicationMaterials Research Society Symposium Proceedings - Nature of Design-Utilizing Biology's Portfolio
PublisherMaterials Research Society
Number of pages5
ISBN (Print)9781605604411
StatePublished - 2007
Externally publishedYes
EventNature of Design-Utilizing Biology's Portfolio - 2007 MRS Spring Meeting - San Francisco, CA, United States
Duration: 9 Apr 200713 Apr 2007

Publication series

NameMaterials Research Society Symposium Proceedings
ISSN (Print)0272-9172


ConferenceNature of Design-Utilizing Biology's Portfolio - 2007 MRS Spring Meeting
Country/TerritoryUnited States
CitySan Francisco, CA


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