Novel integrated electrochemical nano-biochip for toxicity detection in water

Rachela Popovtzer; Tova Neufeld; Dvora Biran; Eliora Z. Ron; Judith Rishpon; Yosi Shacham-Diamand

doi:10.1021/nl0503227

Novel integrated electrochemical nano-biochip for toxicity detection in water

Rachela Popovtzer, Tova Neufeld, Dvora Biran, Eliora Z. Ron, Judith Rishpon, Yosi Shacham-Diamand

Tel Aviv University

Research output: Contribution to journal › Article › peer-review

84 Scopus citations

Abstract

An electrochemical nano-biochip for water toxicity detection is presented. We describe chip design, fabrication, and performance. Bacteria, which have been genetically engineered to respond to environmental stress, act as a sensor element and trigger a sequence of processes, which leads to generation of electrical current. This novel, portable and miniature device provides rapid and sensitive real-time electrochemical detection of acute toxicity in water. A clear signal is produced within less than 10 min of exposure to various concentrations of toxicants, or to stress conditions, with a direct correlation between the toxicant concentration and the induced current.

Original language	English
Pages (from-to)	1023-1027
Number of pages	5
Journal	Nano Letters
Volume	5
Issue number	6
DOIs	https://doi.org/10.1021/nl0503227
State	Published - Jun 2005
Externally published	Yes

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10.1021/nl0503227

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AU - Shacham-Diamand, Yosi

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Novel integrated electrochemical nano-biochip for toxicity detection in water

Abstract

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