Novel integrated electrochemical nano-biochip for toxicity detection in water

Rachela Popovtzer, Tova Neufeld, Dvora Biran, Eliora Z. Ron, Judith Rishpon, Yosi Shacham-Diamand

Research output: Contribution to journalArticlepeer-review

83 Scopus citations

Abstract

An electrochemical nano-biochip for water toxicity detection is presented. We describe chip design, fabrication, and performance. Bacteria, which have been genetically engineered to respond to environmental stress, act as a sensor element and trigger a sequence of processes, which leads to generation of electrical current. This novel, portable and miniature device provides rapid and sensitive real-time electrochemical detection of acute toxicity in water. A clear signal is produced within less than 10 min of exposure to various concentrations of toxicants, or to stress conditions, with a direct correlation between the toxicant concentration and the induced current.

Original languageEnglish
Pages (from-to)1023-1027
Number of pages5
JournalNano Letters
Volume5
Issue number6
DOIs
StatePublished - Jun 2005
Externally publishedYes

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