Abstract
Novel chiral electro-oxidizable dicarbazoles functionalized by N- succinimidyl/phthalimidyl or pentafluorophenyl carboxylates 6a-c were synthesized from L-lysine methyl ester 1 and characterized electrochemically. The corresponding chiral polycarbazole films 8a-c constitute polymers suitable for covalent grafting of proteins, as demonstrated for bovine serum albumin as a model compound. (C) 2000 Elsevier Science Ltd.
Original language | English |
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Pages (from-to) | 3725-3729 |
Number of pages | 5 |
Journal | Tetrahedron Letters |
Volume | 41 |
Issue number | 19 |
DOIs | |
State | Published - 6 May 2000 |
Externally published | Yes |
Bibliographical note
Funding Information:This work was generously supported by the Institute for Applied Biosciences (Ben-Gurion University of the Negev) through internal granting and a post-doctorate fellowship (K.P.) as well as by the Ministry of Science and the Arts. J.-P. Lellouche wishes to thank the Rashi Foundation for its financial support through the granting of a Guastella fellowship.
Funding
This work was generously supported by the Institute for Applied Biosciences (Ben-Gurion University of the Negev) through internal granting and a post-doctorate fellowship (K.P.) as well as by the Ministry of Science and the Arts. J.-P. Lellouche wishes to thank the Rashi Foundation for its financial support through the granting of a Guastella fellowship.
Funders | Funder number |
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Institute for Applied Biosciences | |
Ministry of Science and the Arts | |
Rashi Foundation |
Keywords
- Biosensors
- Bovine serum albumin
- Chiral polymers
- Polycarbazoles
- Protein attachment