TY - JOUR
T1 - Noncontact speckle-based optical sensor for detection of glucose concentration using magneto-optic effect
AU - Ozana, Nisan
AU - Beiderman, Yevgeny
AU - Anand, Arun
AU - Javidi, Baharam
AU - Polani, Sagi
AU - Schwarz, Ariel
AU - Shemer, Amir
AU - Garcia, Javier
AU - Zalevsky, Zeev
N1 - Publisher Copyright:
© 2016 Society of Photo-Optical Instrumentation Engineers (SPIE).
PY - 2016/6/1
Y1 - 2016/6/1
N2 - We experimentally verify a speckle-based technique for noncontact measurement of glucose concentration in the bloodstream. The final device is intended to be a single wristwatch-style device containing a laser, a camera, and an alternating current (ac) electromagnet generated by a solenoid. The experiments presented are performed in vitro as proof of the concept. When a glucose substance is inserted into a solenoid generating an ac magnetic field, it exhibits Faraday rotation, which affects the temporal changes of the secondary speckle pattern distributions. The temporal frequency resulting from the ac magnetic field was found to have a lock-in amplification role, which increased the observability of the relatively small magneto-optic effect. Experimental results to support the proposed concept are presented.
AB - We experimentally verify a speckle-based technique for noncontact measurement of glucose concentration in the bloodstream. The final device is intended to be a single wristwatch-style device containing a laser, a camera, and an alternating current (ac) electromagnet generated by a solenoid. The experiments presented are performed in vitro as proof of the concept. When a glucose substance is inserted into a solenoid generating an ac magnetic field, it exhibits Faraday rotation, which affects the temporal changes of the secondary speckle pattern distributions. The temporal frequency resulting from the ac magnetic field was found to have a lock-in amplification role, which increased the observability of the relatively small magneto-optic effect. Experimental results to support the proposed concept are presented.
KW - biophotonics
KW - magneto-optics
KW - polarization
KW - speckle
UR - http://www.scopus.com/inward/record.url?scp=84973375282&partnerID=8YFLogxK
U2 - 10.1117/1.JBO.21.6.065001
DO - 10.1117/1.JBO.21.6.065001
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C2 - 27251076
AN - SCOPUS:84973375282
SN - 1083-3668
VL - 21
JO - Journal of Biomedical Optics
JF - Journal of Biomedical Optics
IS - 6
M1 - 065001
ER -