Noncontact speckle-based optical sensor for detection of glucose concentration using magneto-optic effect

Nisan Ozana, Yevgeny Beiderman, Arun Anand, Baharam Javidi, Sagi Polani, Ariel Schwarz, Amir Shemer, Javier Garcia, Zeev Zalevsky

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

We experimentally verify a speckle-based technique for noncontact measurement of glucose concentration in the bloodstream. The final device is intended to be a single wristwatch-style device containing a laser, a camera, and an alternating current (ac) electromagnet generated by a solenoid. The experiments presented are performed in vitro as proof of the concept. When a glucose substance is inserted into a solenoid generating an ac magnetic field, it exhibits Faraday rotation, which affects the temporal changes of the secondary speckle pattern distributions. The temporal frequency resulting from the ac magnetic field was found to have a lock-in amplification role, which increased the observability of the relatively small magneto-optic effect. Experimental results to support the proposed concept are presented.

Original languageEnglish
Article number065001
JournalJournal of Biomedical Optics
Volume21
Issue number6
DOIs
StatePublished - 1 Jun 2016

Bibliographical note

Publisher Copyright:
© 2016 Society of Photo-Optical Instrumentation Engineers (SPIE).

Keywords

  • biophotonics
  • magneto-optics
  • polarization
  • speckle

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