No relationship between maternal iron status and postpartum depression in two samples in China

Rinat Armony-Sivan, Jie Shao, Ming Li, Gengli Zhao, Zhengyan Zhao, Guobing Xu, Min Zhou, Jianying Zhan, Yang Bian, Chai Ji, Xing Li, Yaping Jiang, Zhixiang Zhang, Blair J. Richards, Twila Tardif, Betsy Lozoff

Research output: Contribution to journalArticlepeer-review

45 Scopus citations

Abstract

Maternal iron status is thought to be related to postpartum depressive symptoms. The purpose of the present study was to evaluate the relationship between pre- and postnatal maternal iron status and depressive symptoms in pilot (n=137) and confirmatory (n=567) samples of Chinese women. Iron status was evaluated at mid- and late pregnancy and 3 days postpartum. The Edinburgh Postnatal Depression Scale (EPDS) was used to assess maternal postpartum depression 2448 hours after delivery and 6 weeks later. In the pilot sample, correlations between early- and late-pregnancy maternal Hb and EPDS scores at 6 weeks were r=0.07 and -0.01, respectively (nonsignificant). In the confirmatory sample, the correlations between maternal iron measures (Hb, MCV, ZPP, ferritin, sTfR, and sTfR Index) in mid- or late pregnancy or 3 days postpartum and EPDS scores shortly after delivery or at 6 weeks were also low (r values 0.10). EPDS scores in anemic and nonanemic mothers did not differ, regardless of sample or timing of maternal iron status assessment. In addition, women with or without possible PPD were similar in iron status in both samples. Thus, there was no relationship between maternal iron status and postpartum depression in these samples.

Original languageEnglish
Article number521431
JournalJournal of Pregnancy
Volume2012
DOIs
StatePublished - 2012
Externally publishedYes

Fingerprint

Dive into the research topics of 'No relationship between maternal iron status and postpartum depression in two samples in China'. Together they form a unique fingerprint.

Cite this