NMR Characterization of Erodible Copolymers

Robert Langer; Eyal Ron; Edith Mathiowitz; George Mathiowitz; Abram Domb

doi:10.1021/ma00009a024

NMR Characterization of Erodible Copolymers

Robert Langer, Eyal Ron, Edith Mathiowitz, George Mathiowitz, Abram Domb

Research output: Contribution to journal › Article › peer-review

56 Scopus citations

Abstract

NMR spectroscopy analysis coupled with information from X-ray diffraction allowed understanding of the nature of the erosion phenomena for degradable polymers. The determination of copolymer composition and comonomer sequence distributions in anhydride copolymers of aliphatic and aromatic dicarboxylic acids is discussed. From high-field nuclear magnetic resonance spectroscopy data the copolymers’ sequence was determined. In addition, the characterization of molecular weight distributions by intrinsic viscosity measurements and by gel permeation chromatography (GPC) using the universal calibration procedure was made.

Original language	English
Pages (from-to)	2278-2282
Number of pages	5
Journal	Macromolecules
Volume	24
Issue number	9
DOIs	https://doi.org/10.1021/ma00009a024
State	Published - 1 Apr 1991
Externally published	Yes

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10.1021/ma00009a024

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title = "NMR Characterization of Erodible Copolymers",

abstract = "NMR spectroscopy analysis coupled with information from X-ray diffraction allowed understanding of the nature of the erosion phenomena for degradable polymers. The determination of copolymer composition and comonomer sequence distributions in anhydride copolymers of aliphatic and aromatic dicarboxylic acids is discussed. From high-field nuclear magnetic resonance spectroscopy data the copolymers{\textquoteright} sequence was determined. In addition, the characterization of molecular weight distributions by intrinsic viscosity measurements and by gel permeation chromatography (GPC) using the universal calibration procedure was made.",

author = "Robert Langer and Eyal Ron and Edith Mathiowitz and George Mathiowitz and Abram Domb",

year = "1991",

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doi = "10.1021/ma00009a024",

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T1 - NMR Characterization of Erodible Copolymers

AU - Langer, Robert

AU - Ron, Eyal

AU - Mathiowitz, Edith

AU - Mathiowitz, George

AU - Domb, Abram

PY - 1991/4/1

Y1 - 1991/4/1

N2 - NMR spectroscopy analysis coupled with information from X-ray diffraction allowed understanding of the nature of the erosion phenomena for degradable polymers. The determination of copolymer composition and comonomer sequence distributions in anhydride copolymers of aliphatic and aromatic dicarboxylic acids is discussed. From high-field nuclear magnetic resonance spectroscopy data the copolymers’ sequence was determined. In addition, the characterization of molecular weight distributions by intrinsic viscosity measurements and by gel permeation chromatography (GPC) using the universal calibration procedure was made.

AB - NMR spectroscopy analysis coupled with information from X-ray diffraction allowed understanding of the nature of the erosion phenomena for degradable polymers. The determination of copolymer composition and comonomer sequence distributions in anhydride copolymers of aliphatic and aromatic dicarboxylic acids is discussed. From high-field nuclear magnetic resonance spectroscopy data the copolymers’ sequence was determined. In addition, the characterization of molecular weight distributions by intrinsic viscosity measurements and by gel permeation chromatography (GPC) using the universal calibration procedure was made.

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NMR Characterization of Erodible Copolymers

Abstract

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