Abstract
Nitriles are shown to react with C,N-diacylimines 2, generated in situ from 1 or 4 in the presence of Lewis acids, to produce 4-amidooxazoles 5 and 6 in good to excellent yield. Diamides are sometimes also produced. The reaction was followed by NMR spectroscopy, and mechanistic pathways are discussed.
| Original language | English |
|---|---|
| Pages (from-to) | 5225-5229 |
| Number of pages | 5 |
| Journal | Journal of Organic Chemistry |
| Volume | 55 |
| Issue number | 18 |
| DOIs | |
| State | Published - Aug 1990 |
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