Abstract
To the Editor: We are concerned that the study by Levran et al. (Oct. 25, 1990, issue)1 suggests an inappropriately negative view of the value of embryo cryopreservation associated with in vitro fertilization. The reported results could have been influenced by numerous factors, including random variation, a suboptimal technique of freezing, and the use of infertile women as oocyte donors. A certain percentage of embryos do not, of course, survive cryopreservation. However, survival as evidenced by cleavage of zygotes frozen and thawed (n = 639) or by preservation of at least 50 percent of the blastomeres of cleaved embryos frozen.
Original language | English |
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Pages (from-to) | 1043-1045 |
Number of pages | 3 |
Journal | New England Journal of Medicine |
Volume | 325 |
Issue number | 14 |
DOIs | |
State | Published - 3 Oct 1991 |
Externally published | Yes |