In recent years, infiltrating materials into the human body has become a great challenge many researches are facing. In medicine and cosmetics today, there are materials which are administrated to patients by injection only. The main challenge with topical medication is penetrating the skin barrier. The skin is an effective barrier between the body and the outside environment, which prevents foreign materials entering the body easily. However, reducing the size of the desired materials might help their skin penetration ability. Recently nanoparticles (NPs) are being evaluated for use in many fields like chemistry, biology, medicine, physics and optics. The technique used in this work for forming organic NPs (ONPs) is the application of sonic waves to an aqueous solution, known as sonochemistry. To investigate the physical penetration depth of ONPs into the human body, we first developed a novel optical technique for detecting NPs within tissues. The detection of NPs is done by the extraction and investigation of the reemitted light phase.
|Title of host publication||Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications VII|
|Editors||Ramesh Raghavachari, Samuel Achilefu|
|State||Published - 2015|
|Event||Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications VII - San Francisco, United States|
Duration: 8 Feb 2015 → 10 Feb 2015
|Name||Progress in Biomedical Optics and Imaging - Proceedings of SPIE|
|Conference||Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications VII|
|Period||8/02/15 → 10/02/15|
Bibliographical notePublisher Copyright:
© 2015 SPIE.
- optical iterative method
- optical properties
- organic nanoparticles
- participating media