New generation super alloy candidates for medical applications: Corrosion behavior, cation release and biological evaluation

L. Reclaru; R. Ziegenhagen; R. E. Unger; P. Y. Eschler; F. Constantin

doi:10.1016/j.msec.2014.09.027

New generation super alloy candidates for medical applications: Corrosion behavior, cation release and biological evaluation

L. Reclaru, R. Ziegenhagen, R. E. Unger, P. Y. Eschler, F. Constantin

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Three super alloy candidates (X1 CrNiMoMnW24-22-6-3-2 N, NiCr21 MoNbFe 8-3-5 AlTi, CoNiCr 35-20 Mo 10 BTi) for a prolonged contact with skin are evaluated in comparison with two reference austenitic stainless steels 316L and 904L. Several electrochemical parameters were measured and determined (E_oc, E_corr, i_corr, b_a, b_c, E_b, R_p, E_crevand coulometric analysis) in order to compare the corrosion behavior. The cation release evaluation and in vitro biological characterization also were performed. In terms of corrosion, the results reveal that the 904L steels presented the best behavior followed by the super austenitic steel X1 CrNiMoMnW 24-22-6-3-2 N. For the other two super alloys (NiCr and CoNiCr types alloys) tested in different conditions (annealed, work hardened and work hardened + age hardened) it was found that their behavior to corrosion wasweak and close to the other reference stainless steel, 316L. Regarding the extraction a mixture of cations in relatively high concentrations was noted and therefore a cocktail effect was not excluded. The results obtained in the biological assays WST-1 and TNF-alpha were in correlation with the corrosion and extraction evaluation.

Original language	English
Pages (from-to)	411-420
Number of pages	10
Journal	Materials Science and Engineering C
Volume	45
DOIs	https://doi.org/10.1016/j.msec.2014.09.027
State	Published - 1 Dec 2014
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2014 Elsevier B.V. All rights reserved.

Keywords

904L and 316L
Alloys X1 CrNiMoMnW 24-22-6-3-2 N NiCr21
Biological assays WST-1 and TNF-alpha
Cation release
Corrosion (generalized, crevice, pitting)
Cytotoxic test
Hela cell line
ICAM-1 induction in HUVEC
L-929
Microstructures
MoNbFe 8-3-5 AlTi CoNiCr 35-20 Mo 10 BTi

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10.1016/j.msec.2014.09.027

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title = "New generation super alloy candidates for medical applications: Corrosion behavior, cation release and biological evaluation",

abstract = "Three super alloy candidates (X1 CrNiMoMnW24-22-6-3-2 N, NiCr21 MoNbFe 8-3-5 AlTi, CoNiCr 35-20 Mo 10 BTi) for a prolonged contact with skin are evaluated in comparison with two reference austenitic stainless steels 316L and 904L. Several electrochemical parameters were measured and determined (Eoc, Ecorr, icorr, ba, bc, Eb, Rp, Ecrevand coulometric analysis) in order to compare the corrosion behavior. The cation release evaluation and in vitro biological characterization also were performed. In terms of corrosion, the results reveal that the 904L steels presented the best behavior followed by the super austenitic steel X1 CrNiMoMnW 24-22-6-3-2 N. For the other two super alloys (NiCr and CoNiCr types alloys) tested in different conditions (annealed, work hardened and work hardened + age hardened) it was found that their behavior to corrosion wasweak and close to the other reference stainless steel, 316L. Regarding the extraction a mixture of cations in relatively high concentrations was noted and therefore a cocktail effect was not excluded. The results obtained in the biological assays WST-1 and TNF-alpha were in correlation with the corrosion and extraction evaluation.",

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author = "L. Reclaru and R. Ziegenhagen and Unger, {R. E.} and Eschler, {P. Y.} and F. Constantin",

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AU - Eschler, P. Y.

AU - Constantin, F.

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N2 - Three super alloy candidates (X1 CrNiMoMnW24-22-6-3-2 N, NiCr21 MoNbFe 8-3-5 AlTi, CoNiCr 35-20 Mo 10 BTi) for a prolonged contact with skin are evaluated in comparison with two reference austenitic stainless steels 316L and 904L. Several electrochemical parameters were measured and determined (Eoc, Ecorr, icorr, ba, bc, Eb, Rp, Ecrevand coulometric analysis) in order to compare the corrosion behavior. The cation release evaluation and in vitro biological characterization also were performed. In terms of corrosion, the results reveal that the 904L steels presented the best behavior followed by the super austenitic steel X1 CrNiMoMnW 24-22-6-3-2 N. For the other two super alloys (NiCr and CoNiCr types alloys) tested in different conditions (annealed, work hardened and work hardened + age hardened) it was found that their behavior to corrosion wasweak and close to the other reference stainless steel, 316L. Regarding the extraction a mixture of cations in relatively high concentrations was noted and therefore a cocktail effect was not excluded. The results obtained in the biological assays WST-1 and TNF-alpha were in correlation with the corrosion and extraction evaluation.

AB - Three super alloy candidates (X1 CrNiMoMnW24-22-6-3-2 N, NiCr21 MoNbFe 8-3-5 AlTi, CoNiCr 35-20 Mo 10 BTi) for a prolonged contact with skin are evaluated in comparison with two reference austenitic stainless steels 316L and 904L. Several electrochemical parameters were measured and determined (Eoc, Ecorr, icorr, ba, bc, Eb, Rp, Ecrevand coulometric analysis) in order to compare the corrosion behavior. The cation release evaluation and in vitro biological characterization also were performed. In terms of corrosion, the results reveal that the 904L steels presented the best behavior followed by the super austenitic steel X1 CrNiMoMnW 24-22-6-3-2 N. For the other two super alloys (NiCr and CoNiCr types alloys) tested in different conditions (annealed, work hardened and work hardened + age hardened) it was found that their behavior to corrosion wasweak and close to the other reference stainless steel, 316L. Regarding the extraction a mixture of cations in relatively high concentrations was noted and therefore a cocktail effect was not excluded. The results obtained in the biological assays WST-1 and TNF-alpha were in correlation with the corrosion and extraction evaluation.

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New generation super alloy candidates for medical applications: Corrosion behavior, cation release and biological evaluation

Abstract

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Keywords

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