Neuroleptic effects on electrodermal responsivity to soft tones and loud noise in schizophrenia

Michael Foster Green; Keith H. Nuechterlein

doi:10.1016/0165-1781(88)90143-6

Neuroleptic effects on electrodermal responsivity to soft tones and loud noise in schizophrenia

Michael Foster Green
, Keith H. Nuechterlein

University of California at Los Angeles

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Electrodermal procedures have consistently yielded two groups of schizophrenic patients-responders and nonresponders-on the basis of their electrodermal responsivity to auditory stimuli. The reliability of this finding has proved to be a cornerstone of autonomic research in schizophrenia. Previous investigators have reported that neuroleptic medications have little or no effect on electrodermal responsivity to mild tones. The current research found that patients receiving neuroleptics with high anticholinergic properties showed significantly less electrodermal responsivity compared with those receiving low anticholinergic neuroleptics. This was true for both loud and mild auditory stimuli.

Original language	English
Pages (from-to)	79-86
Number of pages	8
Journal	Psychiatry Research
Volume	24
Issue number	1
DOIs	https://doi.org/10.1016/0165-1781(88)90143-6
State	Published - Apr 1988
Externally published	Yes

Bibliographical note

Funding Information:
Acknowledgment. The authors thank Gudrun von Berg, Amelia Arria, Lisa Herman, Meggin Hollister, Sharon Smith, Nita Mize, and especially Donna Gaier for their assistance with data collection and the preparation of this manuscript. This work was supported in part by NIMH Research Grant MH-42344 to Dr. Green. The laboratory and diagnostic training was supported by NIMH Clinical Research Center Grant MH-3091 I (Robert P. Liberman, P.I.)..

Funding

Acknowledgment. The authors thank Gudrun von Berg, Amelia Arria, Lisa Herman, Meggin Hollister, Sharon Smith, Nita Mize, and especially Donna Gaier for their assistance with data collection and the preparation of this manuscript. This work was supported in part by NIMH Research Grant MH-42344 to Dr. Green. The laboratory and diagnostic training was supported by NIMH Clinical Research Center Grant MH-3091 I (Robert P. Liberman, P.I.)..

Funders	Funder number
National Institute of Mental Health	P30MH030911, MH-3091 I, MH-42344

Keywords

Electrodermal responsivity
anticholinergic effects
neuroleptic medications

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/0165-1781(88)90143-6

Cite this

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title = "Neuroleptic effects on electrodermal responsivity to soft tones and loud noise in schizophrenia",

abstract = "Electrodermal procedures have consistently yielded two groups of schizophrenic patients-responders and nonresponders-on the basis of their electrodermal responsivity to auditory stimuli. The reliability of this finding has proved to be a cornerstone of autonomic research in schizophrenia. Previous investigators have reported that neuroleptic medications have little or no effect on electrodermal responsivity to mild tones. The current research found that patients receiving neuroleptics with high anticholinergic properties showed significantly less electrodermal responsivity compared with those receiving low anticholinergic neuroleptics. This was true for both loud and mild auditory stimuli.",

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note = "Funding Information: Acknowledgment. The authors thank Gudrun von Berg, Amelia Arria, Lisa Herman, Meggin Hollister, Sharon Smith, Nita Mize, and especially Donna Gaier for their assistance with data collection and the preparation of this manuscript. This work was supported in part by NIMH Research Grant MH-42344 to Dr. Green. The laboratory and diagnostic training was supported by NIMH Clinical Research Center Grant MH-3091 I (Robert P. Liberman, P.I.)..",

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Neuroleptic effects on electrodermal responsivity to soft tones and loud noise in schizophrenia

Abstract

Bibliographical note

Funding

Keywords

UN SDGs

Access to Document

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