Nematicidal activity against Aphelenchoides besseyi and Ditylenchus destructor of three biflavonoids, isolated from roots of Stellera chamaejasme

Hui Jin; Haiyan Cui; Xiaoyan Yang; Lihong Xu; Xudong Li; Rentao Liu; Zhiqiang Yan; Xiuzhuang Li; Weili Zheng; Yuhui Zhao; Xiaoxia Song; Lihua Zhong; Anxiang Su; Bo Qin

doi:10.1016/j.aspen.2018.11.013

Nematicidal activity against Aphelenchoides besseyi and Ditylenchus destructor of three biflavonoids, isolated from roots of Stellera chamaejasme

Hui Jin, Haiyan Cui, Xiaoyan Yang, Lihong Xu, Xudong Li, Rentao Liu, Zhiqiang Yan, Xiuzhuang Li, Weili Zheng, Yuhui Zhao, Xiaoxia Song, Lihua Zhong, Anxiang Su, Bo Qin

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

Aphelenchoides besseyi and Ditylenchus destructor can cause serious problems for a number of important agricultural crops and vegetables. In this study, the ethanol extract of Stellera chamaejasme L. roots showed strong nematicidal activity against Aphelenchoides besseyi and Ditylenchus destructor. By using a bioactivity-driven fractionation, three biflavonoids were isolated from the extract and their structures were identified by mass and nuclear magnetic resonance spectral data. Nematicidal activity bioassays revealed that isoneochamaejasmin A had the strongest nematicidal activity against A. besseyi and D. destructor with LC₅₀ values of 2.32 and 0.18 mM at 72 h, respectively. Chamaejasmenin B displayed weaker nematicidal activity against A. besseyi with an LC₅₀ value of 3.94 mM at 72 h. Neochamaejasmin B induced the lowest mortality against D. destructor with an LC₅₀ values of 15.6 mM at 72 h. These results suggested that the kind and position of substitutions and the relative configuration of 2-H/3-H and 2”-H/3”-H could be considered as important factors responsible for the nematicidal activity of these purified C-3/C-3″ biflavonoids.

Original language	English
Pages (from-to)	1473-1478
Number of pages	6
Journal	Journal of Asia-Pacific Entomology
Volume	21
Issue number	4
DOIs	https://doi.org/10.1016/j.aspen.2018.11.013
State	Published - Dec 2018
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2018 Korean Society of Applied Entomology

Funding

The authors thank Prof. Frank Stermitz for English edition. This work was financially supported by the National Natural Science Foundation of China (No. 31772668 , 81601647 , 31560037 , 21775154 and 31570354 ), the National Key Research and Development Program ( 2017YFD0200804-05 ), Cooperation Program to Gansu Province of Lanzhou Branch of the Chinese Academy of Sciences , CAS “Light of West China” Program, the Open Project Program for State Key Laboratory of Grassland Agro-ecosystem of Lanzhou University ( SKLGAE201704 ), the Open Project Program of Breeding Base for State Key Laboratory of Land Degradation and Ecological Restoration of North-western China/ Key Laboratory for Restoration and Reconstruction of Degraded Ecosystem in North-western China of Ministry of Education ( 2017KF009 ), and Around five top priorities program of “One-Three-Five” Strategic Planning of Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences . The authors thank Prof. Frank Stermitz for English edition. This work was financially supported by the National Natural Science Foundation of China (No. 31772668, 81601647, 31560037, 21775154 and 31570354), the National Key Research and Development Program (2017YFD0200804-05), Cooperation Program to Gansu Province of Lanzhou Branch of the Chinese Academy of Sciences, CAS “Light of West China” Program, the Open Project Program for State Key Laboratory of Grassland Agro-ecosystem of Lanzhou University (SKLGAE201704), the Open Project Program of Breeding Base for State Key Laboratory of Land Degradation and Ecological Restoration of North-western China/ Key Laboratory for Restoration and Reconstruction of Degraded Ecosystem in North-western China of Ministry of Education (2017KF009), and Around five top priorities program of “One-Three-Five” Strategic Planning of Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences.

Funders	Funder number
Cooperation Program to Gansu Province of Lanzhou Branch of the Chinese Academy of Sciences
Open Project Program for State Key Laboratory of Grassland Agro-ecosystem of Lanzhou University
Research and Development
Lanzhou University	SKLGAE201704
National Natural Science Foundation of China	31772668, 31570354, 21775154, 31560037, 81601647
Ministry of Education of the People's Republic of China	2017KF009
Chinese Academy of Sciences
Ministry of Education
Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences
National Key Research and Development Program of China	2017YFD0200804-05

Keywords

Aphelenchoides besseyi
Biflavonoids
Ditylenchus destructor
Nematicidal compounds
Plant extract

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10.1016/j.aspen.2018.11.013

Cite this

Jin, H., Cui, H., Yang, X., Xu, L., Li, X., Liu, R., Yan, Z., Li, X., Zheng, W., Zhao, Y., Song, X., Zhong, L., Su, A., & Qin, B. (2018). Nematicidal activity against Aphelenchoides besseyi and Ditylenchus destructor of three biflavonoids, isolated from roots of Stellera chamaejasme. Journal of Asia-Pacific Entomology, 21(4), 1473-1478. https://doi.org/10.1016/j.aspen.2018.11.013

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title = "Nematicidal activity against Aphelenchoides besseyi and Ditylenchus destructor of three biflavonoids, isolated from roots of Stellera chamaejasme",

abstract = "Aphelenchoides besseyi and Ditylenchus destructor can cause serious problems for a number of important agricultural crops and vegetables. In this study, the ethanol extract of Stellera chamaejasme L. roots showed strong nematicidal activity against Aphelenchoides besseyi and Ditylenchus destructor. By using a bioactivity-driven fractionation, three biflavonoids were isolated from the extract and their structures were identified by mass and nuclear magnetic resonance spectral data. Nematicidal activity bioassays revealed that isoneochamaejasmin A had the strongest nematicidal activity against A. besseyi and D. destructor with LC50 values of 2.32 and 0.18 mM at 72 h, respectively. Chamaejasmenin B displayed weaker nematicidal activity against A. besseyi with an LC50 value of 3.94 mM at 72 h. Neochamaejasmin B induced the lowest mortality against D. destructor with an LC50 values of 15.6 mM at 72 h. These results suggested that the kind and position of substitutions and the relative configuration of 2-H/3-H and 2”-H/3”-H could be considered as important factors responsible for the nematicidal activity of these purified C-3/C-3″ biflavonoids.",

keywords = "Aphelenchoides besseyi, Biflavonoids, Ditylenchus destructor, Nematicidal compounds, Plant extract",

author = "Hui Jin and Haiyan Cui and Xiaoyan Yang and Lihong Xu and Xudong Li and Rentao Liu and Zhiqiang Yan and Xiuzhuang Li and Weili Zheng and Yuhui Zhao and Xiaoxia Song and Lihua Zhong and Anxiang Su and Bo Qin",

note = "Publisher Copyright: {\textcopyright} 2018 Korean Society of Applied Entomology",

year = "2018",

month = dec,

doi = "10.1016/j.aspen.2018.11.013",

language = "אנגלית",

volume = "21",

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Jin, H, Cui, H, Yang, X, Xu, L, Li, X, Liu, R, Yan, Z, Li, X, Zheng, W, Zhao, Y, Song, X, Zhong, L, Su, A & Qin, B 2018, 'Nematicidal activity against Aphelenchoides besseyi and Ditylenchus destructor of three biflavonoids, isolated from roots of Stellera chamaejasme', Journal of Asia-Pacific Entomology, vol. 21, no. 4, pp. 1473-1478. https://doi.org/10.1016/j.aspen.2018.11.013

TY - JOUR

T1 - Nematicidal activity against Aphelenchoides besseyi and Ditylenchus destructor of three biflavonoids, isolated from roots of Stellera chamaejasme

AU - Jin, Hui

AU - Cui, Haiyan

AU - Yang, Xiaoyan

AU - Xu, Lihong

AU - Li, Xudong

AU - Liu, Rentao

AU - Yan, Zhiqiang

AU - Li, Xiuzhuang

AU - Zheng, Weili

AU - Zhao, Yuhui

AU - Song, Xiaoxia

AU - Zhong, Lihua

AU - Su, Anxiang

AU - Qin, Bo

PY - 2018/12

Y1 - 2018/12

N2 - Aphelenchoides besseyi and Ditylenchus destructor can cause serious problems for a number of important agricultural crops and vegetables. In this study, the ethanol extract of Stellera chamaejasme L. roots showed strong nematicidal activity against Aphelenchoides besseyi and Ditylenchus destructor. By using a bioactivity-driven fractionation, three biflavonoids were isolated from the extract and their structures were identified by mass and nuclear magnetic resonance spectral data. Nematicidal activity bioassays revealed that isoneochamaejasmin A had the strongest nematicidal activity against A. besseyi and D. destructor with LC50 values of 2.32 and 0.18 mM at 72 h, respectively. Chamaejasmenin B displayed weaker nematicidal activity against A. besseyi with an LC50 value of 3.94 mM at 72 h. Neochamaejasmin B induced the lowest mortality against D. destructor with an LC50 values of 15.6 mM at 72 h. These results suggested that the kind and position of substitutions and the relative configuration of 2-H/3-H and 2”-H/3”-H could be considered as important factors responsible for the nematicidal activity of these purified C-3/C-3″ biflavonoids.

AB - Aphelenchoides besseyi and Ditylenchus destructor can cause serious problems for a number of important agricultural crops and vegetables. In this study, the ethanol extract of Stellera chamaejasme L. roots showed strong nematicidal activity against Aphelenchoides besseyi and Ditylenchus destructor. By using a bioactivity-driven fractionation, three biflavonoids were isolated from the extract and their structures were identified by mass and nuclear magnetic resonance spectral data. Nematicidal activity bioassays revealed that isoneochamaejasmin A had the strongest nematicidal activity against A. besseyi and D. destructor with LC50 values of 2.32 and 0.18 mM at 72 h, respectively. Chamaejasmenin B displayed weaker nematicidal activity against A. besseyi with an LC50 value of 3.94 mM at 72 h. Neochamaejasmin B induced the lowest mortality against D. destructor with an LC50 values of 15.6 mM at 72 h. These results suggested that the kind and position of substitutions and the relative configuration of 2-H/3-H and 2”-H/3”-H could be considered as important factors responsible for the nematicidal activity of these purified C-3/C-3″ biflavonoids.

KW - Aphelenchoides besseyi

KW - Biflavonoids

KW - Ditylenchus destructor

KW - Nematicidal compounds

KW - Plant extract

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SN - 1226-8615

VL - 21

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JO - Journal of Asia-Pacific Entomology

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ER -

Nematicidal activity against Aphelenchoides besseyi and Ditylenchus destructor of three biflavonoids, isolated from roots of Stellera chamaejasme

Abstract

Bibliographical note

Funding

Keywords

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