TY - JOUR
T1 - Neisseria meningitidis and cytomegalovirus simultaneous detection in the filmarray meningitis/encephalitis panel and its clinical relevance
AU - Sorek, Nadav
AU - Ashkenazi, Shai
AU - Livni, Gilat
AU - Ben-Zvi, Haim
N1 - Publisher Copyright:
© 2019
PY - 2019
Y1 - 2019
N2 - A BioFire FilmArray Meningitis/Encephalitis test was performed on a 7-month old child suspected for bacterial meningitis. Two pathogens were detected, Neisseria meningitidis and cytomegalovirus (CMV). We verified the filmarray meningitis/encephalitis test by pan-bacterial assay to test for Neisseria meningitidis and CMV viral load test for the CMV detection. Pan-bacterial confirmed presence of N. meningitidis, but CMV was not detected by the CMV viral load test. Together with the manifestations of high fever, vomiting, diffuse petechial rash, bulging fontanel, and leukocytosis, it is a clear case of meningococcal meningitis, while CMV detection had no clinical relevance.
AB - A BioFire FilmArray Meningitis/Encephalitis test was performed on a 7-month old child suspected for bacterial meningitis. Two pathogens were detected, Neisseria meningitidis and cytomegalovirus (CMV). We verified the filmarray meningitis/encephalitis test by pan-bacterial assay to test for Neisseria meningitidis and CMV viral load test for the CMV detection. Pan-bacterial confirmed presence of N. meningitidis, but CMV was not detected by the CMV viral load test. Together with the manifestations of high fever, vomiting, diffuse petechial rash, bulging fontanel, and leukocytosis, it is a clear case of meningococcal meningitis, while CMV detection had no clinical relevance.
UR - http://www.scopus.com/inward/record.url?scp=85065873046&partnerID=8YFLogxK
U2 - 10.1016/j.idcr.2019.e00516
DO - 10.1016/j.idcr.2019.e00516
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C2 - 31193598
AN - SCOPUS:85065873046
SN - 2214-2509
VL - 17
JO - IDCases
JF - IDCases
M1 - e00516
ER -
