Nanopalladium grained polymer nanocomposite based sensor for the sensitive determination of Melatonin

Neeraj Kumar, Rosy, Rajendra N. Goyal

Research output: Contribution to journalArticlepeer-review

37 Scopus citations

Abstract

The present work investigates the electrocatalytic properties of the palladium nanoparticles based polymer nanocomposite towards sensing of Melatonin (MEL). The modification protocol involved a single step fabrication and was achieved using cyclic voltammetry. The sensing surface was characterized using voltammetry, FE-SEM, EDX and EIS. Quantitative estimation of MEL has also been carried out using square wave voltammetry in the linear concentration range of 5-100 μM and sensitivity and limit of detection of 0.1235 μA/μM and 0.09 μM respectively have been achieved. The surface modified sensor exhibited almost 3 fold improvement in the sensing properties in comparison to the unmodified surface. The proposed method was also successfully extended for the determination of MEL in commercially available pharmaceutical formulations and human urine samples.

Original languageEnglish
Pages (from-to)18-26
Number of pages9
JournalElectrochimica Acta
Volume211
DOIs
StatePublished - 1 Sep 2016
Externally publishedYes

Bibliographical note

Funding Information:
Two of the authors (Neeraj and Rosy) are thankful to the Ministry of Human Resources Development, New Delhi for the award of Junior and Senior Research Fellowship respectively.

Publisher Copyright:
© 2016 Elsevier Ltd. All rights reserved.

Keywords

  • Melatonin
  • Sensors
  • Voltammetry
  • conducting polymer
  • palladium nano particles
  • reduced graphene oxide

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