Mutation parameters from DNA sequence data using graph theoretic measures on lineage trees

Keyphrases

• B Cells 100%
• DNA Sequencing 100%
• Lineage Tree 100%
• Graph-theoretic Measures 100%
• B Cell Receptor 66%
• Somatic Hypermutation 66%
• Tree Structure 66%
• Clonal Expansion 66%
• Affinity Maturation 33%
• Mutual Information 33%
• Function-based 33%
• Joint Distribution 33%
• Underlying Assumptions 33%
• Birth-death Process 33%
• Spleen 33%
• Binding Properties 33%
• Short Time Scale 33%
• Autoimmune 33%
• Likelihood Function 33%
• Immune Process 33%
• Affinity Selection 33%
• Bioinformatics Methods 33%
• Lethal mutations 33%
• Mutation Rate 33%
• Number of Generations 33%
• Antigenic Stimulation 33%
• Process Simulation 33%
• Autoimmune Process 33%
• Unbiased Estimate 33%
• Phylogenetic Lineages 33%
• Systematic Validation 33%
• Expansion Model 33%
• Likelihood Analysis 33%
• Synthetic Tree 33%

Immunology and Microbiology

• Lineages 100%
• Tree 100%
• DNA Sequence 100%
• B Cell 50%
• Somatic Hypermutation 33%
• B-Cell Receptor 33%
• Affinity Maturation 16%
• Autoimmunity 16%
• Mouse 16%
• Phylogeny 16%
• Lethal Mutation 16%
• Mutation Rate 16%
• Process Model 16%

Agricultural and Biological Sciences

• Lineages 100%
• B Cell 100%
• B-Cell Receptor 66%
• Cladistics 33%
• Mouse 33%
• Autoimmunity 33%