Mutation of single murine acetylcholine receptor subunits reveals differential contribution of P121 to acetylcholine binding and channel opening

Medicine & Life Sciences

• Cholinergic Receptors 100%
• Acetylcholine 84%
• Myasthenic Syndrome, Congenital, Fast-Channel 52%
• Mutation 50%
• Point Mutation 44%
• Congenital Myasthenic Syndromes 35%
• Ligand-Gated Ion Channels 30%
• Xenopus laevis 26%
• Neuromuscular Junction 26%
• Nicotinic Receptors 24%
• Muscle Weakness 24%
• Oocytes 21%
• Signal Transduction 17%
• Binding Sites 17%
• Ligands 15%
• Muscles 13%

Chemical Compounds

• Acetylcholine 96%
• Mutation 76%
• Neuromuscular 21%
• Signal Transduction 16%
• Asymmetry 15%
• Binding Site 10%