Abstract
Previous reports have established that several variables are of prognostic importance in rectal cancer. The information from a Medical Research Council trial in seventeen centres in the United Kingdom was used to assess the simultaneous contribution of several of these factors in a multivariate analysis. In the preoperative assessment mobility of the tumour and the number of quadrants involved were predictive of the likelihood of a curative resection being possible. Among patients who had curative resections, prognosis was influenced by Dukes' classification, height of tumour, histological grade, and venous invasion. A scoring system based on these criteria was constructed and applied to this group of patients. It successfully defined five prognostic groups with 5-year survival rates ranging from 80% to 19%.
| Original language | English |
|---|---|
| Pages (from-to) | 733-736 |
| Number of pages | 4 |
| Journal | The Lancet |
| Volume | 324 |
| Issue number | 8405 |
| DOIs | |
| State | Published - 29 Sep 1984 |
| Externally published | Yes |
