@inproceedings{8c791bf6366c4eedbddcac916eb018f8,
title = "Multiscale (nano-to-micro) design of integrated nanobio systems",
abstract = "The design of devices that incorporate both nanoscale and continuum scale physics is challenging due to the nature of simulation techniques required for each scale. This paper presents a hierarchical approach where micro/mesoscopic models of molecular phenomena are coupled to continuum device descriptions. This method is developed and demonstrated with reference to DNA hybridization on a microcantilever platform. A macroscopic (Langmuir) model of DNA hybridization is coupled to a mesoscopic description that captures the effect of critical parameters such as salt concentration and graft density. Bridging of the two models was achieved by way of a stochastic Master Equation which was transformed into a Fokker-Planck equivalent that can then be solved in a PDE framework.",
keywords = "DNA hybridization, Microfluidics, Nanoscale modeling",
author = "Jenkins, {J. W.} and M. Hagan and A. Chakraborty and S. Sundaram",
year = "2004",
language = "אנגלית",
isbn = "0972842276",
series = "2004 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2004",
pages = "22--25",
editor = "M. Laudon and B. Romanowicz",
booktitle = "2004 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2004",
note = "2004 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2004 ; Conference date: 07-03-2004 Through 11-03-2004",
}