Multifunctional magnetite and silica-magnetite nanoparticles: Synthesis, surface activation and applications in life sciences

Aránzazu Del Campo; Tapas Sen; Jean Paul Lellouche; Ian J. Bruce

doi:10.1016/j.jmmm.2005.01.040

Multifunctional magnetite and silica-magnetite nanoparticles: Synthesis, surface activation and applications in life sciences

Aránzazu Del Campo, Tapas Sen, Jean Paul Lellouche, Ian J. Bruce

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

196 Scopus citations

Abstract

A method for the introduction of amine groups onto the surface of magnetite and silica-coated magnetite nanoparticles has been established based on the condensation of aminopropyltriethoxysilane. Amine-modified particles were grafted with an oligonucleotide and used in the capture of a complimentary sequence. The particles' efficiency at capture was observed to correlate directly with amine group surface density.

Original language	English
Pages (from-to)	33-40
Number of pages	8
Journal	Journal of Magnetism and Magnetic Materials
Volume	293
Issue number	1
DOIs	https://doi.org/10.1016/j.jmmm.2005.01.040
State	Published - May 2005

Bibliographical note

Funding Information:
The authors thank the European Union and FP5 (CHEMAG Project, G5RD-CT-2001-00534) for financial support, Dr. Guidi for the SEM and TEM images and E. Borioni for his help in the experimental work.

Keywords

Alkoxysilanes
DNA immobilisation
Silica-magnetite nanocomposites
Surface modification

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10.1016/j.jmmm.2005.01.040

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abstract = "A method for the introduction of amine groups onto the surface of magnetite and silica-coated magnetite nanoparticles has been established based on the condensation of aminopropyltriethoxysilane. Amine-modified particles were grafted with an oligonucleotide and used in the capture of a complimentary sequence. The particles' efficiency at capture was observed to correlate directly with amine group surface density.",

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note = "Funding Information: The authors thank the European Union and FP5 (CHEMAG Project, G5RD-CT-2001-00534) for financial support, Dr. Guidi for the SEM and TEM images and E. Borioni for his help in the experimental work. ",

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AU - Bruce, Ian J.

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Multifunctional magnetite and silica-magnetite nanoparticles: Synthesis, surface activation and applications in life sciences

Abstract

Bibliographical note

Keywords

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