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Multicolor spectral karotyping of human chromosomes

  • ED Schrock
  • , Manoir S Du
  • , T Veldman
  • , B Schoell
  • , J Wienberg
  • , MA Ferguson-Smith
  • , Y Ning
  • , DH Ledbetter
  • , I Bar-Am
  • , D Soenksen
  • , Y. Garini
  • , T Ried

Research output: Contribution to journalArticlepeer-review

Abstract

The simultaneous and unequivocal discernment of all human chromosomes in different colors would be of significant clinical and biologic importance. Whole-genome scanning by spectral karotyping allowed instantaneous visualization of defined emission spectra for each human chromosome after fluorescence in situ hybridization.
Original languageAmerican English
Pages (from-to)494-497
JournalScience
Volume273
Issue number5274
StatePublished - 1996

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