Multicolor spectral karotyping of human chromosomes

ED Schrock; Manoir S Du; T Veldman; B Schoell; J Wienberg; MA Ferguson-Smith; Y Ning; DH Ledbetter; I Bar-Am; D Soenksen; Y. Garini; T Ried

Multicolor spectral karotyping of human chromosomes

ED Schrock, Manoir S Du, T Veldman, B Schoell, J Wienberg, MA Ferguson-Smith, Y Ning, DH Ledbetter, I Bar-Am, D Soenksen, Y. Garini, T Ried

Department of Physics

Research output: Contribution to journal › Article › peer-review

Abstract

The simultaneous and unequivocal discernment of all human chromosomes in different colors would be of significant clinical and biologic importance. Whole-genome scanning by spectral karotyping allowed instantaneous visualization of defined emission spectra for each human chromosome after fluorescence in situ hybridization.

Original language	American English
Pages (from-to)	494-497
Journal	Science
Volume	273
Issue number	5274
State	Published - 1996

Cite this

@article{4f9e4508c9514d239e02c4e9bdebadb6,

title = "Multicolor spectral karotyping of human chromosomes",

abstract = "The simultaneous and unequivocal discernment of all human chromosomes in different colors would be of significant clinical and biologic importance. Whole-genome scanning by spectral karotyping allowed instantaneous visualization of defined emission spectra for each human chromosome after fluorescence in situ hybridization.",

author = "ED Schrock and Du, {Manoir S} and T Veldman and B Schoell and J Wienberg and MA Ferguson-Smith and Y Ning and DH Ledbetter and I Bar-Am and D Soenksen and Y. Garini and T Ried",

year = "1996",

language = "American English",

volume = "273",

pages = "494--497",

journal = "Science",

issn = "0036-8075",

publisher = "American Association for the Advancement of Science",

number = "5274",

}

TY - JOUR

T1 - Multicolor spectral karotyping of human chromosomes

AU - Schrock, ED

AU - Du, Manoir S

AU - Veldman, T

AU - Schoell, B

AU - Wienberg, J

AU - Ferguson-Smith, MA

AU - Ning, Y

AU - Ledbetter, DH

AU - Bar-Am, I

AU - Soenksen, D

AU - Garini, Y.

AU - Ried, T

PY - 1996

Y1 - 1996

N2 - The simultaneous and unequivocal discernment of all human chromosomes in different colors would be of significant clinical and biologic importance. Whole-genome scanning by spectral karotyping allowed instantaneous visualization of defined emission spectra for each human chromosome after fluorescence in situ hybridization.

AB - The simultaneous and unequivocal discernment of all human chromosomes in different colors would be of significant clinical and biologic importance. Whole-genome scanning by spectral karotyping allowed instantaneous visualization of defined emission spectra for each human chromosome after fluorescence in situ hybridization.

M3 - Article

SN - 0036-8075

VL - 273

SP - 494

EP - 497

JO - Science

JF - Science

IS - 5274

ER -

Multicolor spectral karotyping of human chromosomes

Abstract

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