Abstract
Mammalian Target of Rapamycin (mTOR) is a highly conserved protein kinase that functions as part of two distinct multiprotein complexes to regulate growth and metabolism. This review describes the most important recent advances in the mTOR signaling field. In addition, we provide an overview on the functions of mTOR in different organs, with a special focus on the role of mTOR in whole body energy metabolism.
Original language | English |
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Pages (from-to) | 209-218 |
Number of pages | 10 |
Journal | Current Opinion in Cell Biology |
Volume | 21 |
Issue number | 2 |
DOIs | |
State | Published - Apr 2009 |
Externally published | Yes |
Bibliographical note
Funding Information:We apologize to colleagues whose work we could not describe owing to space limitations. MNH acknowledges support from the Swiss National Science Foundation and the Canton of Basel.
Funding
We apologize to colleagues whose work we could not describe owing to space limitations. MNH acknowledges support from the Swiss National Science Foundation and the Canton of Basel.
Funders | Funder number |
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Canton of Basel | |
Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung | 125348 |