Movies, measurement, and modeling: The three Ms of mechanistic immunology

Colleen Witt, Subhadip Raychaudhuri, Arup K. Chakraborty

Research output: Contribution to journalReview articlepeer-review

17 Scopus citations


Immunological phenomena that were once deduced from genetic, biochemical, and in situ approaches are now being witnessed in living color, in three dimensions, and in real time. The information in time-lapse imaging can provide valuable mechanistic insight into a host of processes, from cell migration to signal transduction. What we need now are methods to quantitate these new visual data and to exploit computational resources and statistical mechanical methods to develop mechanistic models.

Original languageEnglish
Pages (from-to)501-504
Number of pages4
JournalJournal of Experimental Medicine
Issue number4
StatePublished - 21 Feb 2005
Externally publishedYes


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