TY - JOUR
T1 - Movies, measurement, and modeling
T2 - The three Ms of mechanistic immunology
AU - Witt, Colleen
AU - Raychaudhuri, Subhadip
AU - Chakraborty, Arup K.
PY - 2005/2/21
Y1 - 2005/2/21
N2 - Immunological phenomena that were once deduced from genetic, biochemical, and in situ approaches are now being witnessed in living color, in three dimensions, and in real time. The information in time-lapse imaging can provide valuable mechanistic insight into a host of processes, from cell migration to signal transduction. What we need now are methods to quantitate these new visual data and to exploit computational resources and statistical mechanical methods to develop mechanistic models.
AB - Immunological phenomena that were once deduced from genetic, biochemical, and in situ approaches are now being witnessed in living color, in three dimensions, and in real time. The information in time-lapse imaging can provide valuable mechanistic insight into a host of processes, from cell migration to signal transduction. What we need now are methods to quantitate these new visual data and to exploit computational resources and statistical mechanical methods to develop mechanistic models.
UR - http://www.scopus.com/inward/record.url?scp=14244262349&partnerID=8YFLogxK
U2 - 10.1084/jem.20050197
DO - 10.1084/jem.20050197
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C2 - 15728232
AN - SCOPUS:14244262349
SN - 0022-1007
VL - 201
SP - 501
EP - 504
JO - Journal of Experimental Medicine
JF - Journal of Experimental Medicine
IS - 4
ER -