TY - JOUR
T1 - Modification of cytokine secretion following mild emotional stimuli
AU - Mittwoch-Jaffe, Tamar
AU - Shalit, Frances
AU - Srendi, Benjamine
AU - Yehuda, Shlomo
PY - 1995/3/27
Y1 - 1995/3/27
N2 - In the present study, changes in the cytokine system (IL-1β, IL-2, IL-3, IL-6 and TNFα) were assessed following exposure to mild mood induction (negative and positive) in humans. An increase in secretion of TNFα, a decrease in that of IL-2 and of IL-3 with no change in IL-1β and in IL-6 secretion levels, was observed in response to mild negative emotional changes. A reversed cytokine secretion profile was found following positive mood changes, suggesting the hypothalamic-pituitary- adrenal axis and the autonomic nervous system, as possible mediators underlying these effects, specific to the nature of the emotion.
AB - In the present study, changes in the cytokine system (IL-1β, IL-2, IL-3, IL-6 and TNFα) were assessed following exposure to mild mood induction (negative and positive) in humans. An increase in secretion of TNFα, a decrease in that of IL-2 and of IL-3 with no change in IL-1β and in IL-6 secretion levels, was observed in response to mild negative emotional changes. A reversed cytokine secretion profile was found following positive mood changes, suggesting the hypothalamic-pituitary- adrenal axis and the autonomic nervous system, as possible mediators underlying these effects, specific to the nature of the emotion.
KW - Autonomic nervous system
KW - Cytokines
KW - Emotions
KW - Hypothalamic-pituitary-adrenal axis
KW - Il-2
KW - Il-3
KW - Neural modulation
KW - TNF
UR - http://www.scopus.com/inward/record.url?scp=0028957663&partnerID=8YFLogxK
U2 - 10.1097/00001756-199503270-00021
DO - 10.1097/00001756-199503270-00021
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C2 - 7605950
AN - SCOPUS:0028957663
SN - 0959-4965
VL - 6
SP - 789
EP - 792
JO - NeuroReport
JF - NeuroReport
IS - 5
ER -