Model of unequal chromosomal crossing over in DNA sequences

Nikolay V. Dokholyan, Sergey V. Buldyrev, Shlomo Havlin, H. Eugene Stanley

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


It is known that some dimeric tandem repeats (DTR) are very abundant in noncoding DNA. We find that certain DTR length distribution functions in noncoding DNA can be fit by a power law function. We analyze a simplified model of unequal chromosomal crossing over and find that it produces a stable power law length distribution function, with the exponent μ = 2. Although the exponent predicted by this model differs from those observed in nature, we argue that the biophysical process underlying this model provides the major contribution to the DTR length distribution function.

Original languageEnglish
Pages (from-to)594-599
Number of pages6
JournalPhysica A: Statistical Mechanics and its Applications
Issue number1-4
StatePublished - 2 Jan 1998

Bibliographical note

Funding Information:
This work is supported by NIH-HGP.


  • DNA
  • Mutations
  • Repeats


Dive into the research topics of 'Model of unequal chromosomal crossing over in DNA sequences'. Together they form a unique fingerprint.

Cite this