MicroRNAS FOR THE GENERATION OF ASTROCYTES

Chaya Brodie; Aharon Brodie

MicroRNAS FOR THE GENERATION OF ASTROCYTES

Chaya Brodie (Inventor), Aharon Brodie (Inventor)

Research output: Patent

Abstract

A method of generating a population of cells useful for treating a nerve disease or disorder in a subject, the method comprising up-regulating a level of at least one exogenous miRNA in mesenchymal stem cells (MSCs) and/or down-regulating a level of at least one miRNA using a polynucleotide agent that hybridizes to the miRNA, thereby generating the population of cells useful for treating the nerve disease or disorder. Isolated populations of cells with an astrocytic phenotype generated thereby and uses thereof are also provided.

Original language	English
Patent number	US20190015453A1
State	Published - 17 Jan 2019

Bibliographical note

US Patent App. 16/048,676

Cite this

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abstract = "A method of generating a population of cells useful for treating a nerve disease or disorder in a subject, the method comprising up-regulating a level of at least one exogenous miRNA in mesenchymal stem cells (MSCs) and/or down-regulating a level of at least one miRNA using a polynucleotide agent that hybridizes to the miRNA, thereby generating the population of cells useful for treating the nerve disease or disorder. Isolated populations of cells with an astrocytic phenotype generated thereby and uses thereof are also provided.",

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MicroRNAS FOR THE GENERATION OF ASTROCYTES

Abstract

Bibliographical note

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