Microarray: An approach for current drug targets

Virendra S. Gomase; Somnath Tagore; Karbhari V. Kale

doi:10.2174/138920008783884795

Microarray: An approach for current drug targets

Virendra S. Gomase, Somnath Tagore, Karbhari V. Kale

Research output: Contribution to journal › Review article › peer-review

19 Scopus citations

Abstract

Microarrays are a powerful tool has multiple applications both in clinical and cellular and molecular biology arenas. Early assessment of the probable biological importance of drug targets, pharmacogenomics, toxicogenomics and single nucleotide polymorphisms (SNPs). A list of new drug candidates along with proposed targets for intervention is described. Recent advances in the knowledge of microarrays analysis of organisms and the availability of the genomics sequences provide a wide range of novel targets for drug design. This review gives different process of microarray technologies; methods for comparative gene expression study, applications of microarrays in medicine and pharmacogenomics and current drug targets in research, which are relevant to common diseases as they relate to clinical and future perspectives.

Original language	English
Pages (from-to)	221-231
Number of pages	11
Journal	Current Drug Metabolism
Volume	9
Issue number	3
DOIs	https://doi.org/10.2174/138920008783884795
State	Published - Mar 2008
Externally published	Yes

Keywords

Biomarker
DNA arrays
FISH
Gene expression
IHC
Microarrays
Oligonucleotide

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10.2174/138920008783884795

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Microarray: An approach for current drug targets

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Keywords

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