MICROANGIOPATHIC HEMOLYTIC ANEMIA AS PRESENTING SYMPTOM OF GASTRIC ADENOCARCINOMA

Najib Dally; Marat Kashlikov; Raymond Farah

MICROANGIOPATHIC HEMOLYTIC ANEMIA AS PRESENTING SYMPTOM OF GASTRIC ADENOCARCINOMA

Najib Dally, Marat Kashlikov, Raymond Farah

Bar-Ilan University - Azrieli Faculty of Medicine

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Abstract

Metastatic adenocarcinoma presenting as microangiopathic hemolytic anemia (MAHA) is a rare finding. We report the case of a young patient who presented with MAHA as the initial symptom of metastatic gastric adenocarcinoma. Cancer-related microangiopathic hemolytic anemia is a paraneoplastic syndrome characterized by Coombs-negative hemolytic anemia with schistocytes and thrombocytopenia. A high index of suspicion and prompt diagnosis can prevent ulterior deterioration, especially when chemotherapy is the optimal treatment in these cases, which can stop the hemolysis.

Original language	English
Pages (from-to)	212-4, 255
Journal	Harefuah
Volume	155
Issue number	4
State	Published - 1 Apr 2016

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abstract = "Metastatic adenocarcinoma presenting as microangiopathic hemolytic anemia (MAHA) is a rare finding. We report the case of a young patient who presented with MAHA as the initial symptom of metastatic gastric adenocarcinoma. Cancer-related microangiopathic hemolytic anemia is a paraneoplastic syndrome characterized by Coombs-negative hemolytic anemia with schistocytes and thrombocytopenia. A high index of suspicion and prompt diagnosis can prevent ulterior deterioration, especially when chemotherapy is the optimal treatment in these cases, which can stop the hemolysis.",

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AU - Farah, Raymond

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AB - Metastatic adenocarcinoma presenting as microangiopathic hemolytic anemia (MAHA) is a rare finding. We report the case of a young patient who presented with MAHA as the initial symptom of metastatic gastric adenocarcinoma. Cancer-related microangiopathic hemolytic anemia is a paraneoplastic syndrome characterized by Coombs-negative hemolytic anemia with schistocytes and thrombocytopenia. A high index of suspicion and prompt diagnosis can prevent ulterior deterioration, especially when chemotherapy is the optimal treatment in these cases, which can stop the hemolysis.

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MICROANGIOPATHIC HEMOLYTIC ANEMIA AS PRESENTING SYMPTOM OF GASTRIC ADENOCARCINOMA

Abstract

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